Takayasu's Arteritis Associated With Glomerulonephritis: A Case Report

Gaston E. Zilleruelo, Pedro Ferrer, Otto L. Garcia, Marcus Moore, Victoriano Pardo, José Strauss

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26 Scopus citations

Abstract

Takayasu's disease is a non specific arteritis of unknown cause with predilection for the aortic arch and its branches; approximately 20% of those affected are children or adolescents, predominantly females. The purpose of this article is to report the case of a young girl in which the mode of presentation was microscopic hematuria and proteinuria. Subsequently, aortic valvular insufficiency developed and there was evidence of aortitis in the thoracic and abdominal aorta, as well as in the arch. All functional and anatomical cardiac derangements were documented by ultrasound and angiocardiography. Renal biopsies showed progressive glomerular involvement characterized by focal and segmental glomerulonephritis. It is postulated that a common immunologic mechanism was responsible for the aortic and glomerular lesions.

Original languageEnglish (US)
Pages (from-to)1009-1013
Number of pages5
JournalAmerican Journal of Diseases of Children
Volume132
Issue number10
DOIs
StatePublished - Oct 1978

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Zilleruelo, G. E., Ferrer, P., Garcia, O. L., Moore, M., Pardo, V., & Strauss, J. (1978). Takayasu's Arteritis Associated With Glomerulonephritis: A Case Report. American Journal of Diseases of Children, 132(10), 1009-1013. https://doi.org/10.1001/archpedi.1978.02120350073015