Abstract
Introduction. Type 4 renal tubular acidosis is an uncommon clinical manifestation of systemic lupus erythematosus and has been reported to portend a poor prognosis. To the best of our knowledge, this is the first case report which highlights the successful management of a patient with systemic lupus erythematosus complicated by type 4 renal tubular acidosis who did not do poorly. Case presentation. A 44-year-old Hispanic woman developed a non-anion gap hyperkalemic metabolic acidosis consistent with type 4 renal tubular acidosis while being treated in the hospital for recently diagnosed systemic lupus erythematosus with multi-organ involvement. She responded well to treatment with corticosteroids, hydroxychloroquine and mycophenolate mofetil. Normal renal function was achieved prior to discharge and remained normal at the patient's one-month follow-up examination. Conclusion: This case increases awareness of an uncommon association between systemic lupus erythematosus and type 4 renal tubular acidosis and suggests a positive impact of early diagnosis and appropriate immunosuppressive treatment on the patient's outcome.
| Original language | English |
|---|---|
| Article number | 114 |
| Journal | Journal of Medical Case Reports |
| Volume | 5 |
| DOIs | |
| State | Published - Mar 31 2011 |
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ASJC Scopus subject areas
- Medicine(all)
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Systemic lupus erythematosus associated with type 4 renal tubular acidosis : A case report and review of the literature. / Porteous, Haldane; Morgan, Nadia; Lanfranco, Julio; Garcia-Buitrago, Monica; Young, Larry; Lenz, Oliver.
In: Journal of Medical Case Reports, Vol. 5, 114, 31.03.2011.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Systemic lupus erythematosus associated with type 4 renal tubular acidosis
T2 - A case report and review of the literature
AU - Porteous, Haldane
AU - Morgan, Nadia
AU - Lanfranco, Julio
AU - Garcia-Buitrago, Monica
AU - Young, Larry
AU - Lenz, Oliver
PY - 2011/3/31
Y1 - 2011/3/31
N2 - Introduction. Type 4 renal tubular acidosis is an uncommon clinical manifestation of systemic lupus erythematosus and has been reported to portend a poor prognosis. To the best of our knowledge, this is the first case report which highlights the successful management of a patient with systemic lupus erythematosus complicated by type 4 renal tubular acidosis who did not do poorly. Case presentation. A 44-year-old Hispanic woman developed a non-anion gap hyperkalemic metabolic acidosis consistent with type 4 renal tubular acidosis while being treated in the hospital for recently diagnosed systemic lupus erythematosus with multi-organ involvement. She responded well to treatment with corticosteroids, hydroxychloroquine and mycophenolate mofetil. Normal renal function was achieved prior to discharge and remained normal at the patient's one-month follow-up examination. Conclusion: This case increases awareness of an uncommon association between systemic lupus erythematosus and type 4 renal tubular acidosis and suggests a positive impact of early diagnosis and appropriate immunosuppressive treatment on the patient's outcome.
AB - Introduction. Type 4 renal tubular acidosis is an uncommon clinical manifestation of systemic lupus erythematosus and has been reported to portend a poor prognosis. To the best of our knowledge, this is the first case report which highlights the successful management of a patient with systemic lupus erythematosus complicated by type 4 renal tubular acidosis who did not do poorly. Case presentation. A 44-year-old Hispanic woman developed a non-anion gap hyperkalemic metabolic acidosis consistent with type 4 renal tubular acidosis while being treated in the hospital for recently diagnosed systemic lupus erythematosus with multi-organ involvement. She responded well to treatment with corticosteroids, hydroxychloroquine and mycophenolate mofetil. Normal renal function was achieved prior to discharge and remained normal at the patient's one-month follow-up examination. Conclusion: This case increases awareness of an uncommon association between systemic lupus erythematosus and type 4 renal tubular acidosis and suggests a positive impact of early diagnosis and appropriate immunosuppressive treatment on the patient's outcome.
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U2 - 10.1186/1752-1947-5-114
DO - 10.1186/1752-1947-5-114
M3 - Article
C2 - 21435204
AN - SCOPUS:79953111834
VL - 5
JO - Journal of Medical Case Reports
JF - Journal of Medical Case Reports
SN - 1752-1947
M1 - 114
ER -