Systemic lupus erythematosus and pregnancy

Elaine Tozman, M. B. Urowitz, D. D. Gladman

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

In a review of 250 patients with systemic lupus erythematosus (SLE), there were 24 pregnancies among 18 women. Of these, there were 16 completed pregnancies, 1 stillbirth, 1 spontaneous abortion, and 6 therapeutic abortions. Fetal loss, excluding therapeutic abortion, was 16.6%. Of the 13 patients with active disease at conception, SLE remained active in 11, and became inactive in 2. Of the 11 women with inactive disease at conception, disease remained inactive in 10. Even in the cases of previously serious renal or central nervous system involvement, inactive disease at conception was not associated with disease recurrence. Such patients may attempt pregnancy with favorable prognosis for both mother and child.

Original languageEnglish
Pages (from-to)624-632
Number of pages9
JournalJournal of Rheumatology
Volume7
Issue number5
StatePublished - Dec 1 1980
Externally publishedYes

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Systemic Lupus Erythematosus
Pregnancy
Therapeutic Abortion
Stillbirth
Spontaneous Abortion
Central Nervous System
Mothers
Kidney
Recurrence

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Tozman, E., Urowitz, M. B., & Gladman, D. D. (1980). Systemic lupus erythematosus and pregnancy. Journal of Rheumatology, 7(5), 624-632.

Systemic lupus erythematosus and pregnancy. / Tozman, Elaine; Urowitz, M. B.; Gladman, D. D.

In: Journal of Rheumatology, Vol. 7, No. 5, 01.12.1980, p. 624-632.

Research output: Contribution to journalArticle

Tozman, E, Urowitz, MB & Gladman, DD 1980, 'Systemic lupus erythematosus and pregnancy', Journal of Rheumatology, vol. 7, no. 5, pp. 624-632.
Tozman E, Urowitz MB, Gladman DD. Systemic lupus erythematosus and pregnancy. Journal of Rheumatology. 1980 Dec 1;7(5):624-632.
Tozman, Elaine ; Urowitz, M. B. ; Gladman, D. D. / Systemic lupus erythematosus and pregnancy. In: Journal of Rheumatology. 1980 ; Vol. 7, No. 5. pp. 624-632.
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