System for on-and off-axis volumetric OCT imaging and ray tracing aberrometry of the crystalline lens

Marco Ruggeri, Siobhan Williams, Bianca Maceo Heilman, Yue Yao, Yu Cherng Chang, Ashik Mohamed, N. Geetha Sravani, Heather Durkee, Cornelis Rowaan, Alex Gonzalez, Arthur Ho, Jean-Marie A Parel, Fabrice Manns

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

We present a new in vitro instrument for measuring shape and wavefront aberrations of the primate crystalline lens, both on-and off-axis, while simulating accommodation with a motorized lens stretching system. The instrument merges spectral domain optical coherence tomography (SD-OCT) imaging and ray tracing aberrometry using an approach that senses wavefront aberrations of the lens with the OCT probing beam. Accuracy and repeatability of aberration measurements were quantified. Preliminary experiments on two human and four cynomolgus monkey lenses demonstrate the ability of the system to measure the lens shape, spherical aberration and peripheral defocus, and their changes during simulated accommodation.

Original languageEnglish (US)
Article number332332
Pages (from-to)3834-3851
Number of pages18
JournalBiomedical Optics Express
Volume9
Issue number8
DOIs
StatePublished - Aug 1 2018

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

Fingerprint Dive into the research topics of 'System for on-and off-axis volumetric OCT imaging and ray tracing aberrometry of the crystalline lens'. Together they form a unique fingerprint.

  • Cite this

    Ruggeri, M., Williams, S., Heilman, B. M., Yao, Y., Chang, Y. C., Mohamed, A., Sravani, N. G., Durkee, H., Rowaan, C., Gonzalez, A., Ho, A., Parel, J-M. A., & Manns, F. (2018). System for on-and off-axis volumetric OCT imaging and ray tracing aberrometry of the crystalline lens. Biomedical Optics Express, 9(8), 3834-3851. [332332]. https://doi.org/10.1364/BOE.9.003834