Abstract
We present a new in vitro instrument for measuring shape and wavefront aberrations of the primate crystalline lens, both on-and off-axis, while simulating accommodation with a motorized lens stretching system. The instrument merges spectral domain optical coherence tomography (SD-OCT) imaging and ray tracing aberrometry using an approach that senses wavefront aberrations of the lens with the OCT probing beam. Accuracy and repeatability of aberration measurements were quantified. Preliminary experiments on two human and four cynomolgus monkey lenses demonstrate the ability of the system to measure the lens shape, spherical aberration and peripheral defocus, and their changes during simulated accommodation.
| Original language | English (US) |
|---|---|
| Article number | 332332 |
| Pages (from-to) | 3834-3851 |
| Number of pages | 18 |
| Journal | Biomedical Optics Express |
| Volume | 9 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 1 2018 |
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ASJC Scopus subject areas
- Biotechnology
- Atomic and Molecular Physics, and Optics
Cite this
System for on-and off-axis volumetric OCT imaging and ray tracing aberrometry of the crystalline lens. / Ruggeri, Marco; Williams, Siobhan; Heilman, Bianca Maceo; Yao, Yue; Chang, Yu Cherng; Mohamed, Ashik; Sravani, N. Geetha; Durkee, Heather; Rowaan, Cornelis; Gonzalez, Alex; Ho, Arthur; Parel, Jean-Marie A; Manns, Fabrice.
In: Biomedical Optics Express, Vol. 9, No. 8, 332332, 01.08.2018, p. 3834-3851.Research output: Contribution to journal › Article
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TY - JOUR
T1 - System for on-and off-axis volumetric OCT imaging and ray tracing aberrometry of the crystalline lens
AU - Ruggeri, Marco
AU - Williams, Siobhan
AU - Heilman, Bianca Maceo
AU - Yao, Yue
AU - Chang, Yu Cherng
AU - Mohamed, Ashik
AU - Sravani, N. Geetha
AU - Durkee, Heather
AU - Rowaan, Cornelis
AU - Gonzalez, Alex
AU - Ho, Arthur
AU - Parel, Jean-Marie A
AU - Manns, Fabrice
PY - 2018/8/1
Y1 - 2018/8/1
N2 - We present a new in vitro instrument for measuring shape and wavefront aberrations of the primate crystalline lens, both on-and off-axis, while simulating accommodation with a motorized lens stretching system. The instrument merges spectral domain optical coherence tomography (SD-OCT) imaging and ray tracing aberrometry using an approach that senses wavefront aberrations of the lens with the OCT probing beam. Accuracy and repeatability of aberration measurements were quantified. Preliminary experiments on two human and four cynomolgus monkey lenses demonstrate the ability of the system to measure the lens shape, spherical aberration and peripheral defocus, and their changes during simulated accommodation.
AB - We present a new in vitro instrument for measuring shape and wavefront aberrations of the primate crystalline lens, both on-and off-axis, while simulating accommodation with a motorized lens stretching system. The instrument merges spectral domain optical coherence tomography (SD-OCT) imaging and ray tracing aberrometry using an approach that senses wavefront aberrations of the lens with the OCT probing beam. Accuracy and repeatability of aberration measurements were quantified. Preliminary experiments on two human and four cynomolgus monkey lenses demonstrate the ability of the system to measure the lens shape, spherical aberration and peripheral defocus, and their changes during simulated accommodation.
UR - http://www.scopus.com/inward/record.url?scp=85051283779&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85051283779&partnerID=8YFLogxK
U2 - 10.1364/BOE.9.003834
DO - 10.1364/BOE.9.003834
M3 - Article
AN - SCOPUS:85051283779
VL - 9
SP - 3834
EP - 3851
JO - Biomedical Optics Express
JF - Biomedical Optics Express
SN - 2156-7085
IS - 8
M1 - 332332
ER -