Abstract
Helical-chiral analogues of imidazopyridine-2-yilidene were synthesized from 2-aza[6]helicene. The energies of their frontier orbitals were analyzed by the density functional theory calculations. The exceedingly large extension of NHC's π system by helicene annelation significantly enhanced the π electron-accepting properties of the carbene center while the strong σ electron-donating properties of imidazopyridine-2-yilidenes were retained.
Original language | English (US) |
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Article number | 152143 |
Journal | Tetrahedron Letters |
Volume | 61 |
Issue number | 30 |
DOIs | |
State | Published - Jul 23 2020 |
Keywords
- Catalyst design
- Computational chemistry
- Electronic properties
- Helicene
- N-heterocyclic carbenes
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry