Synthesis and surface chemistry study of a new amphiphilic PAMAM dendrimer

Guodong Sui, Miodrag Micic, Qun Huo, Roger M. Leblanc

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


A new disk-shaped amphiphilic dendrimer has been synthesized by attaching sixty-four 12-hydroxy-dodecanoic acid chains to a fourth generation poly(amido amine) (PAMAM) dendrimer core. Surface pressure and surface potential-area isotherm measurements have shown that the dendrimer forms a stable monolayer at the air/water interface with limiting molecular area of 160 angstrom2/molecule. This small area relative to the huge size of the dendrimer suggests that the dendrimer molecules form an edge-on disk-shaped structure at the air/water interface. The topography of the dendrimer monolayer was observed by Brewster angle microscopy (BAM) at air/water interface as well as by environmental scanning electron microscopy (ESEM) as a Langmuir-Blodgett film. The striplike monolayer domains observed from BAM images correspond to the monolayer topography as observed from ESEM images.

Original languageEnglish (US)
Pages (from-to)7847-7851
Number of pages5
Issue number20
StatePublished - Oct 3 2000

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry


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