Synapses between neurons regenerate accurately after destruction of ensheathing glial cells in the leech

Ellen J. Elliott, Kenneth J. Muller

Research output: Contribution to journalArticle

12 Scopus citations


Individual glial cells that ensheathe axons in the central nervous system of the leech were destroyed by intracellular injection of protease. The axons were then severed, and regeneration by particular neurons was studied physiologically and morphologically. Although certain axons sprouted more in the absence of the glial cell, functional synapses were accurately regenerated with normal frequency.

Original languageEnglish (US)
Pages (from-to)1260-1262
Number of pages3
Issue number4537
StatePublished - Jan 1 1982
Externally publishedYes


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