Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma

Jesse A. Green; Rafael Amaro; Jamie S. Barkin

doi:10.1023/A:1005638924929

Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma

Jesse A. Green, Rafael Amaro, Jamie S. Barkin

Medicine

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

A population-based, case-control study to investigate the possible association between gastroesophageal reflux (GER) and adenocarcinoma of the esophagus and gastric cardia was performed. It demonstrated an odds ratio of 7.7 for esophageal adenocarcinoma in patients with GER symptoms. The frequency, severity, and duration of symptoms correlated with an increased risk of esophageal adenocarcinoma. A weaker association was noted for GER and adenocarcinoma of the gastric cardia. No association surfaced between GER and squamous cell carcinoma of the esophagus.

Original language	English (US)
Pages (from-to)	2367-2368
Number of pages	2
Journal	Digestive Diseases and Sciences
Volume	45
Issue number	12
DOIs	https://doi.org/10.1023/A:1005638924929
State	Published - Dec 1 2000

Keywords

Adenocarcinoma
Gastroesophageal reflux

ASJC Scopus subject areas

Gastroenterology

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