Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma

Jesse A. Green; Rafael Amaro; Jamie S Barkin

doi:10.1023/A:1005638924929

Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma

Jesse A. Green, Rafael Amaro, Jamie S Barkin

Medicine

Research output: Contribution to journal › Article

17 Scopus citations

Abstract

A population-based, case-control study to investigate the possible association between gastroesophageal reflux (GER) and adenocarcinoma of the esophagus and gastric cardia was performed. It demonstrated an odds ratio of 7.7 for esophageal adenocarcinoma in patients with GER symptoms. The frequency, severity, and duration of symptoms correlated with an increased risk of esophageal adenocarcinoma. A weaker association was noted for GER and adenocarcinoma of the gastric cardia. No association surfaced between GER and squamous cell carcinoma of the esophagus.

Original language	English
Pages (from-to)	2367-2368
Number of pages	2
Journal	Digestive Diseases and Sciences
Volume	45
Issue number	12
DOIs	https://doi.org/10.1023/A:1005638924929
State	Published - Dec 1 2000

Fingerprint

Keywords

Adenocarcinoma
Gastroesophageal reflux

ASJC Scopus subject areas

Gastroenterology

Cite this

Green, J. A., Amaro, R., & Barkin, J. S. (2000). Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. Digestive Diseases and Sciences, 45(12), 2367-2368. https://doi.org/10.1023/A:1005638924929

@article{f28bf4bcfcba49e7b573f182844a78ed,

title = "Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma",

abstract = "A population-based, case-control study to investigate the possible association between gastroesophageal reflux (GER) and adenocarcinoma of the esophagus and gastric cardia was performed. It demonstrated an odds ratio of 7.7 for esophageal adenocarcinoma in patients with GER symptoms. The frequency, severity, and duration of symptoms correlated with an increased risk of esophageal adenocarcinoma. A weaker association was noted for GER and adenocarcinoma of the gastric cardia. No association surfaced between GER and squamous cell carcinoma of the esophagus.",

keywords = "Adenocarcinoma, Gastroesophageal reflux",

author = "Green, {Jesse A.} and Rafael Amaro and Barkin, {Jamie S}",

year = "2000",

month = dec

day = "1",

doi = "10.1023/A:1005638924929",

language = "English",

volume = "45",

pages = "2367--2368",

journal = "Digestive Diseases and Sciences",

issn = "0163-2116",

publisher = "Plenum Publishers",

number = "12",

}

TY - JOUR

T1 - Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma

AU - Green, Jesse A.

AU - Amaro, Rafael

AU - Barkin, Jamie S

PY - 2000/12/1

Y1 - 2000/12/1

N2 - A population-based, case-control study to investigate the possible association between gastroesophageal reflux (GER) and adenocarcinoma of the esophagus and gastric cardia was performed. It demonstrated an odds ratio of 7.7 for esophageal adenocarcinoma in patients with GER symptoms. The frequency, severity, and duration of symptoms correlated with an increased risk of esophageal adenocarcinoma. A weaker association was noted for GER and adenocarcinoma of the gastric cardia. No association surfaced between GER and squamous cell carcinoma of the esophagus.

AB - A population-based, case-control study to investigate the possible association between gastroesophageal reflux (GER) and adenocarcinoma of the esophagus and gastric cardia was performed. It demonstrated an odds ratio of 7.7 for esophageal adenocarcinoma in patients with GER symptoms. The frequency, severity, and duration of symptoms correlated with an increased risk of esophageal adenocarcinoma. A weaker association was noted for GER and adenocarcinoma of the gastric cardia. No association surfaced between GER and squamous cell carcinoma of the esophagus.

KW - Adenocarcinoma

KW - Gastroesophageal reflux

UR - http://www.scopus.com/inward/record.url?scp=0034465576&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034465576&partnerID=8YFLogxK

U2 - 10.1023/A:1005638924929

DO - 10.1023/A:1005638924929

M3 - Article

C2 - 11258559

AN - SCOPUS:0034465576

VL - 45

SP - 2367

EP - 2368

JO - Digestive Diseases and Sciences

JF - Digestive Diseases and Sciences

SN - 0163-2116

IS - 12

ER -

Access to Document

10.1023/A:1005638924929