Sympathetic postganglionic unmyelinated axons in the rat peripheral nervous system

D. Chad, Walter G Bradley, C. Rasool, P. Good, S. Reichlin, J. Zivin

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We determined the contribution made to the unmyelinated axon population of the rat peripheral nervous system by sympathetic paravertebral ganglion cells. Sympathectomy, achieved by administration of guanethidine to neonatal rats, led to atrophy of the sympathetic paravertebral ganglion chain, a 95% decrease in peripheral nerve norepinephrine, and loss of 20 to 26% of the unmyelinated axons in a cutaneous nerve (sural), a muscular nerve (nerve to soleus), and a mixed nerve (sciatic). These data indicate that up to a quarter of the total population of peripheral nerve unmyelinated axons are sympathetic ganglia-derived.

Original languageEnglish
Pages (from-to)841-847
Number of pages7
JournalNeurology
Volume33
Issue number7
StatePublished - Aug 25 1983
Externally publishedYes

Fingerprint

Sympathetic Ganglia
Peripheral Nervous System
Axons
Peripheral Nerves
Guanethidine
Sural Nerve
Sympathectomy
Sciatic Nerve
Population
Atrophy
Norepinephrine
Skin

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Chad, D., Bradley, W. G., Rasool, C., Good, P., Reichlin, S., & Zivin, J. (1983). Sympathetic postganglionic unmyelinated axons in the rat peripheral nervous system. Neurology, 33(7), 841-847.

Sympathetic postganglionic unmyelinated axons in the rat peripheral nervous system. / Chad, D.; Bradley, Walter G; Rasool, C.; Good, P.; Reichlin, S.; Zivin, J.

In: Neurology, Vol. 33, No. 7, 25.08.1983, p. 841-847.

Research output: Contribution to journalArticle

Chad, D, Bradley, WG, Rasool, C, Good, P, Reichlin, S & Zivin, J 1983, 'Sympathetic postganglionic unmyelinated axons in the rat peripheral nervous system', Neurology, vol. 33, no. 7, pp. 841-847.
Chad D, Bradley WG, Rasool C, Good P, Reichlin S, Zivin J. Sympathetic postganglionic unmyelinated axons in the rat peripheral nervous system. Neurology. 1983 Aug 25;33(7):841-847.
Chad, D. ; Bradley, Walter G ; Rasool, C. ; Good, P. ; Reichlin, S. ; Zivin, J. / Sympathetic postganglionic unmyelinated axons in the rat peripheral nervous system. In: Neurology. 1983 ; Vol. 33, No. 7. pp. 841-847.
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