Sustained Striatal Activity Predicts Eudaimonic Well-Being and Cortisol Output

Aaron Heller, Carien M. van Reekum, Stacey M. Schaefer, Regina C. Lapate, Barry T. Radler, Carol D. Ryff, Richard J. Davidson

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Eudaimonic well-being-a sense of purpose, meaning, and engagement with life-is protective against psychopathology and predicts physical health, including lower levels of the stress hormone cortisol. Although it has been suggested that the ability to engage the neural circuitry of reward may promote well-being and mediate the relationship between well-being and health, this hypothesis has remained untested. To test this hypothesis, we had participants view positive, neutral, and negative images while fMRI data were collected. Individuals with sustained activity in the striatum and dorsolateral prefrontal cortex to positive stimuli over the course of the scan session reported greater well-being and had lower cortisol output. This suggests that sustained engagement of reward circuitry in response to positive events underlies well-being and adaptive regulation of the hypothalamic-pituitary-adrenal axis.

Original languageEnglish (US)
Pages (from-to)2191-2200
Number of pages10
JournalPsychological Science
Volume24
Issue number11
DOIs
StatePublished - Nov 2013
Externally publishedYes

Fingerprint

Corpus Striatum
Reward
Hydrocortisone
Aptitude
Health
Prefrontal Cortex
Psychopathology
Magnetic Resonance Imaging
Hormones
Well-being
Cortisol

Keywords

  • neuroimaging
  • rewards
  • well-being

ASJC Scopus subject areas

  • Psychology(all)
  • Arts and Humanities (miscellaneous)

Cite this

Heller, A., van Reekum, C. M., Schaefer, S. M., Lapate, R. C., Radler, B. T., Ryff, C. D., & Davidson, R. J. (2013). Sustained Striatal Activity Predicts Eudaimonic Well-Being and Cortisol Output. Psychological Science, 24(11), 2191-2200. https://doi.org/10.1177/0956797613490744

Sustained Striatal Activity Predicts Eudaimonic Well-Being and Cortisol Output. / Heller, Aaron; van Reekum, Carien M.; Schaefer, Stacey M.; Lapate, Regina C.; Radler, Barry T.; Ryff, Carol D.; Davidson, Richard J.

In: Psychological Science, Vol. 24, No. 11, 11.2013, p. 2191-2200.

Research output: Contribution to journalArticle

Heller, A, van Reekum, CM, Schaefer, SM, Lapate, RC, Radler, BT, Ryff, CD & Davidson, RJ 2013, 'Sustained Striatal Activity Predicts Eudaimonic Well-Being and Cortisol Output', Psychological Science, vol. 24, no. 11, pp. 2191-2200. https://doi.org/10.1177/0956797613490744
Heller A, van Reekum CM, Schaefer SM, Lapate RC, Radler BT, Ryff CD et al. Sustained Striatal Activity Predicts Eudaimonic Well-Being and Cortisol Output. Psychological Science. 2013 Nov;24(11):2191-2200. https://doi.org/10.1177/0956797613490744
Heller, Aaron ; van Reekum, Carien M. ; Schaefer, Stacey M. ; Lapate, Regina C. ; Radler, Barry T. ; Ryff, Carol D. ; Davidson, Richard J. / Sustained Striatal Activity Predicts Eudaimonic Well-Being and Cortisol Output. In: Psychological Science. 2013 ; Vol. 24, No. 11. pp. 2191-2200.
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