Susceptibility of the Bacteroides fragilis group in the United States: Analysis by site of isolation

G. J. Cuchural, F. P. Tally, N. V. Jacobus, K. Aldridge, Timothy Cleary, S. M. Finegold, G. Hill, P. Iannini, J. P. O'Keefe, C. Pierson, D. Crook, T. Russo, D. Hecht

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

An ongoing survey of the susceptibility of the Bacteroides fragilis group of bacteria was continued at New England Medical Center in 1984 and 1985. A total of 1,229 strains were obtained from eight centers in the United States. These results were compared with those for 1,847 isolates tested in 1981 through 1983. The most active β-lactam drugs were imipenem and ticarcillin-clavulanic acid (Timentin), which had a less than 1% resistance rate. No metronidazole- or chloramphenicol-resistant isolates were found during the 5 years of the study. Isolates obtained from blood, perinatal, and bone sites of infection were more resistant to a variety of antimicrobial agents. Susceptibility patterns of the members of the B. fragilis group varied at the eight hospitals and among species. These data indicate the need for determining the susceptibility patterns for the B. fragilis group of organisms at each hospital.

Original languageEnglish
Pages (from-to)717-722
Number of pages6
JournalAntimicrobial Agents and Chemotherapy
Volume32
Issue number5
StatePublished - Jan 1 1988
Externally publishedYes

Fingerprint

Bacteroides fragilis
Lactams
New England
Imipenem
Metronidazole
Chloramphenicol
Anti-Infective Agents
Bacteria
Bone and Bones
Infection
Pharmaceutical Preparations
ticarcillin-clavulanic acid

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Cuchural, G. J., Tally, F. P., Jacobus, N. V., Aldridge, K., Cleary, T., Finegold, S. M., ... Hecht, D. (1988). Susceptibility of the Bacteroides fragilis group in the United States: Analysis by site of isolation. Antimicrobial Agents and Chemotherapy, 32(5), 717-722.

Susceptibility of the Bacteroides fragilis group in the United States : Analysis by site of isolation. / Cuchural, G. J.; Tally, F. P.; Jacobus, N. V.; Aldridge, K.; Cleary, Timothy; Finegold, S. M.; Hill, G.; Iannini, P.; O'Keefe, J. P.; Pierson, C.; Crook, D.; Russo, T.; Hecht, D.

In: Antimicrobial Agents and Chemotherapy, Vol. 32, No. 5, 01.01.1988, p. 717-722.

Research output: Contribution to journalArticle

Cuchural, GJ, Tally, FP, Jacobus, NV, Aldridge, K, Cleary, T, Finegold, SM, Hill, G, Iannini, P, O'Keefe, JP, Pierson, C, Crook, D, Russo, T & Hecht, D 1988, 'Susceptibility of the Bacteroides fragilis group in the United States: Analysis by site of isolation', Antimicrobial Agents and Chemotherapy, vol. 32, no. 5, pp. 717-722.
Cuchural GJ, Tally FP, Jacobus NV, Aldridge K, Cleary T, Finegold SM et al. Susceptibility of the Bacteroides fragilis group in the United States: Analysis by site of isolation. Antimicrobial Agents and Chemotherapy. 1988 Jan 1;32(5):717-722.
Cuchural, G. J. ; Tally, F. P. ; Jacobus, N. V. ; Aldridge, K. ; Cleary, Timothy ; Finegold, S. M. ; Hill, G. ; Iannini, P. ; O'Keefe, J. P. ; Pierson, C. ; Crook, D. ; Russo, T. ; Hecht, D. / Susceptibility of the Bacteroides fragilis group in the United States : Analysis by site of isolation. In: Antimicrobial Agents and Chemotherapy. 1988 ; Vol. 32, No. 5. pp. 717-722.
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