Survival of children and young adults with skin cancer: Analysis of a population-based Florida cancer registry: 1981-2013

Erin C. Dunn, Kevin J. Moore, Feng Miao, Robert Kirsner, Tulay Sengul

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1 Citation (Scopus)

Abstract

Background/Objectives: Although pediatric and young adult skin cancer is uncommon, recent epidemiologic studies have shown pediatric melanoma to be on the rise in the United States. Using a population-based cancer registry, this study examined skin cancer burden and survival disparities in children and young adults. Methods: Linked data from the Florida Cancer Data System and U.S. Census were analyzed to elucidate skin cancer burden distribution and survival disparities in 1543 Florida children (0-9 years), adolescents (10-19 years), and young adults (20-24 years). These disparities were assessed according to sociodemographic groups such as sex, race, ethnicity, and neighborhood level socioeconomic status. A multivariable Cox regression model adjusted for sociodemographic, clinical, and tumor characteristics was used to predict survival. Results: Boys had a slightly greater burden of skin cancer among children (50.9%), whereas girls had the greatest burden for adolescents (54.5%) and young adults (60%). Survival differed between white, black, and other races; 1-year survival was 91.5% for whites and 77.9% for blacks. Average 3- and 5-year survival was comparable for blacks and whites. "Other" race had a 1- and 3-year survival of 96.2%. Conclusion: Because skin cancer is on the rise, it is important to elucidate the burden and determinants associated with survival outcomes to identify high-risk pediatric and young adult populations. Understanding these factors in the Florida pediatric population may provide a base for future endeavors to create culturally competent cancer prevention programs through screening, health promotion, and literacy.

Original languageEnglish (US)
JournalPediatric Dermatology
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Skin Neoplasms
Registries
Young Adult
Survival
Population
Neoplasms
Pediatrics
Health Literacy
Censuses
Health Promotion
Proportional Hazards Models
Information Systems
Social Class
Epidemiologic Studies
Melanoma
hydroquinone

Keywords

  • Cancer registry
  • Florida
  • Melanoma
  • Pediatric skin cancer
  • Young adult skin cancer

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

Cite this

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title = "Survival of children and young adults with skin cancer: Analysis of a population-based Florida cancer registry: 1981-2013",
abstract = "Background/Objectives: Although pediatric and young adult skin cancer is uncommon, recent epidemiologic studies have shown pediatric melanoma to be on the rise in the United States. Using a population-based cancer registry, this study examined skin cancer burden and survival disparities in children and young adults. Methods: Linked data from the Florida Cancer Data System and U.S. Census were analyzed to elucidate skin cancer burden distribution and survival disparities in 1543 Florida children (0-9 years), adolescents (10-19 years), and young adults (20-24 years). These disparities were assessed according to sociodemographic groups such as sex, race, ethnicity, and neighborhood level socioeconomic status. A multivariable Cox regression model adjusted for sociodemographic, clinical, and tumor characteristics was used to predict survival. Results: Boys had a slightly greater burden of skin cancer among children (50.9{\%}), whereas girls had the greatest burden for adolescents (54.5{\%}) and young adults (60{\%}). Survival differed between white, black, and other races; 1-year survival was 91.5{\%} for whites and 77.9{\%} for blacks. Average 3- and 5-year survival was comparable for blacks and whites. {"}Other{"} race had a 1- and 3-year survival of 96.2{\%}. Conclusion: Because skin cancer is on the rise, it is important to elucidate the burden and determinants associated with survival outcomes to identify high-risk pediatric and young adult populations. Understanding these factors in the Florida pediatric population may provide a base for future endeavors to create culturally competent cancer prevention programs through screening, health promotion, and literacy.",
keywords = "Cancer registry, Florida, Melanoma, Pediatric skin cancer, Young adult skin cancer",
author = "Dunn, {Erin C.} and Moore, {Kevin J.} and Feng Miao and Robert Kirsner and Tulay Sengul",
year = "2018",
month = "1",
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doi = "10.1111/pde.13588",
language = "English (US)",
journal = "Pediatric Dermatology",
issn = "0736-8046",
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TY - JOUR

T1 - Survival of children and young adults with skin cancer

T2 - Analysis of a population-based Florida cancer registry: 1981-2013

AU - Dunn, Erin C.

AU - Moore, Kevin J.

AU - Miao, Feng

AU - Kirsner, Robert

AU - Sengul, Tulay

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background/Objectives: Although pediatric and young adult skin cancer is uncommon, recent epidemiologic studies have shown pediatric melanoma to be on the rise in the United States. Using a population-based cancer registry, this study examined skin cancer burden and survival disparities in children and young adults. Methods: Linked data from the Florida Cancer Data System and U.S. Census were analyzed to elucidate skin cancer burden distribution and survival disparities in 1543 Florida children (0-9 years), adolescents (10-19 years), and young adults (20-24 years). These disparities were assessed according to sociodemographic groups such as sex, race, ethnicity, and neighborhood level socioeconomic status. A multivariable Cox regression model adjusted for sociodemographic, clinical, and tumor characteristics was used to predict survival. Results: Boys had a slightly greater burden of skin cancer among children (50.9%), whereas girls had the greatest burden for adolescents (54.5%) and young adults (60%). Survival differed between white, black, and other races; 1-year survival was 91.5% for whites and 77.9% for blacks. Average 3- and 5-year survival was comparable for blacks and whites. "Other" race had a 1- and 3-year survival of 96.2%. Conclusion: Because skin cancer is on the rise, it is important to elucidate the burden and determinants associated with survival outcomes to identify high-risk pediatric and young adult populations. Understanding these factors in the Florida pediatric population may provide a base for future endeavors to create culturally competent cancer prevention programs through screening, health promotion, and literacy.

AB - Background/Objectives: Although pediatric and young adult skin cancer is uncommon, recent epidemiologic studies have shown pediatric melanoma to be on the rise in the United States. Using a population-based cancer registry, this study examined skin cancer burden and survival disparities in children and young adults. Methods: Linked data from the Florida Cancer Data System and U.S. Census were analyzed to elucidate skin cancer burden distribution and survival disparities in 1543 Florida children (0-9 years), adolescents (10-19 years), and young adults (20-24 years). These disparities were assessed according to sociodemographic groups such as sex, race, ethnicity, and neighborhood level socioeconomic status. A multivariable Cox regression model adjusted for sociodemographic, clinical, and tumor characteristics was used to predict survival. Results: Boys had a slightly greater burden of skin cancer among children (50.9%), whereas girls had the greatest burden for adolescents (54.5%) and young adults (60%). Survival differed between white, black, and other races; 1-year survival was 91.5% for whites and 77.9% for blacks. Average 3- and 5-year survival was comparable for blacks and whites. "Other" race had a 1- and 3-year survival of 96.2%. Conclusion: Because skin cancer is on the rise, it is important to elucidate the burden and determinants associated with survival outcomes to identify high-risk pediatric and young adult populations. Understanding these factors in the Florida pediatric population may provide a base for future endeavors to create culturally competent cancer prevention programs through screening, health promotion, and literacy.

KW - Cancer registry

KW - Florida

KW - Melanoma

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KW - Young adult skin cancer

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