Survival hazards analysis in first recurrent breast cancer patients: Seven-year follow-up

S. M. Levy, J. Lee, C. Bagley, Marc E Lippman

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

The purpose of this study was to identify predictors of survival time in first recurrent breast cancer patients, including psychologic as well as biologic factors. Beginning in 1979, 36 women being treated at the National Institutes of Health for histologically proven recurrent disease were enrolled in this prospective study. At the time of data analysis, 24 had died from their malignancy. Through the use of a Cox proportional hazard model, four factors significantly entered the equation predicting survival time in the sample: Patients with a longer disease-free interval, who expressed more joy at baseline testing, who were predicted to live longer by their physicians, and who had fewer metastatic sites tended to live longer with recurrent disease than others in the sample (X2 = 22.9, p < 0.0001). Findings from recent clinical and animal studies suggest that regulatory systems within the organism are linked and potentially influence one another. This study has demonstrated that factors at a number of levels - behavioral, as well as biologic - need to be considered in accounting for disease outcome variance.

Original languageEnglish
Pages (from-to)520-528
Number of pages9
JournalPsychosomatic Medicine
Volume50
Issue number5
StatePublished - Jan 1 1988
Externally publishedYes

Fingerprint

Survival Analysis
Breast Neoplasms
Survival
National Institutes of Health (U.S.)
Biological Factors
Proportional Hazards Models
Prospective Studies
Physicians
Neoplasms

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Psychology(all)

Cite this

Levy, S. M., Lee, J., Bagley, C., & Lippman, M. E. (1988). Survival hazards analysis in first recurrent breast cancer patients: Seven-year follow-up. Psychosomatic Medicine, 50(5), 520-528.

Survival hazards analysis in first recurrent breast cancer patients : Seven-year follow-up. / Levy, S. M.; Lee, J.; Bagley, C.; Lippman, Marc E.

In: Psychosomatic Medicine, Vol. 50, No. 5, 01.01.1988, p. 520-528.

Research output: Contribution to journalArticle

Levy, SM, Lee, J, Bagley, C & Lippman, ME 1988, 'Survival hazards analysis in first recurrent breast cancer patients: Seven-year follow-up', Psychosomatic Medicine, vol. 50, no. 5, pp. 520-528.
Levy, S. M. ; Lee, J. ; Bagley, C. ; Lippman, Marc E. / Survival hazards analysis in first recurrent breast cancer patients : Seven-year follow-up. In: Psychosomatic Medicine. 1988 ; Vol. 50, No. 5. pp. 520-528.
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