Survival and complications of cuffed catheters in children on chronic hemodialysis

Amita Sharma, Gaston Zilleruelo, Carolyn Abitbol, Brenda Montane, Jose Strauss

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Central venous catheters are being increasingly used as hemodialysis vascular access. We evaluated catheter survival, outcome predictors, and complications in a total of 36 catheters used in 13 children and young adults undergoing chronic maintenance hemodialysis through catheter for a duration of 10.4 ± 5.6 months. Reasons for catheter failure were: thrombosis 12 of 36 (33%), infection 6 of 36 (17%), and extrusion 2 of 36 (5.4%). Catheters were lost to infection and thrombosis at 1.1 and 2.2 episodes per 1000 catheter days, respectively. Symptomatic infections, Gram-negative and polymicrobial sepsis increased the risk of catheter failure. Most of the thrombotic episodes occurred in patients with inherent thrombotic tendency. The survival of the 36 catheters was 62% at 1 year. The survival of 13 randomly chosen catheters, 1 from each patient, was 85% at 1 year. The time from insertion to first complication correlated significantly with the outcome (P < 0.03). We conclude that central venous catheters are still associated with a high rate of failure and may be a regular access choice only in a selected patient population with no inherent thrombotic tendency and no other option available for long-term hemodialysis.

Original languageEnglish (US)
Pages (from-to)245-248
Number of pages4
JournalPediatric Nephrology
Issue number3
StatePublished - Apr 1 1999


  • Bacteremia
  • Catheter survival
  • Complications
  • Hemodialysis
  • Outcome predictors
  • Thrombosis
  • Vascular access

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health


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