Surgical treatment of lung cancer in patients with human immunodeficiency virus

Richard J Thurer, Jeffrey P. Jacobs, Fred W. Holland, John R. Cintron

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Background.: Since January 1986, more than 20 patients have been seen at the University of Miami/Jackson Memorial Medical Center and the Miami Veterans Administration Medical Center with concurrent human immunodeficiency virus infection and bronchogenic carcinoma. Four of these patients were treated surgically with curative intent. Methods.: The histories, records, operative reports, and pathology reports of the 4 patients were reviewed. Results.: The 4 surgically treated patients had stage I T1 N0 M0 lung cancer. Three patients had T4 cell counts of less than 200/μL and were managed by lobectomy. These patients died 5, 3 1/2, and 5 months postoperatively. More recently, a fourth patient had a T4 cell count of 963/μL and was treated with wedge resection. He is currently alive 12 months postoperatively. Conclusions.: It is concluded that surgically treated patients with lung cancer, human immunodeficiency virus infection, and T4 cell counts lower than 200/μL have high mortality and morbidity. Although it may be best to base surgical intervention on the stage of the patient's human immunodeficiency virus infection, further analysis is essential to determine which subgroup of human immunodeficiency virus-positive patients, if any, would benefit from surgical treatment of lung cancer.

Original languageEnglish
Pages (from-to)599-602
Number of pages4
JournalThe Annals of Thoracic Surgery
Volume60
Issue number3
DOIs
StatePublished - Jan 1 1995

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Lung Neoplasms
HIV
CD4-Positive T-Lymphocytes
Virus Diseases
Therapeutics
Cell Count
United States Department of Veterans Affairs
Bronchogenic Carcinoma
Pathology
Morbidity
Mortality

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery

Cite this

Surgical treatment of lung cancer in patients with human immunodeficiency virus. / Thurer, Richard J; Jacobs, Jeffrey P.; Holland, Fred W.; Cintron, John R.

In: The Annals of Thoracic Surgery, Vol. 60, No. 3, 01.01.1995, p. 599-602.

Research output: Contribution to journalArticle

Thurer, Richard J ; Jacobs, Jeffrey P. ; Holland, Fred W. ; Cintron, John R. / Surgical treatment of lung cancer in patients with human immunodeficiency virus. In: The Annals of Thoracic Surgery. 1995 ; Vol. 60, No. 3. pp. 599-602.
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