Surgical Therapy for Macular Edema: What We Have Learned through the Decades

Jeong Hun Bae, Hasenin Al-khersan, Nicolas A. Yannuzzi, Murat Hasanreisoglu, Sofia Androudi, Thomas A. Albini, Quan Dong Nguyen

Research output: Contribution to journalReview articlepeer-review


Macular edema is a leading cause of functional visual loss in retinal vascular or ocular inflammatory diseases. Because persistent macular edema can lead to irreversible retinal damage, multi-approached treatment should be considered to achieve complete resolution of macular edema. With an enhanced understanding of its pathophysiology, numerous therapeutic options have been developed for the management of macular edema over the decades. Although medical therapies account for the mainstay of treatment, surgical approaches with vitrectomy can play an important role in the management of macular edema, depending on its mechanism of fluid accumulation. The index review focuses on the efficacy of surgical therapy for macular edema secondary to various ocular diseases including diabetic retinopathy, uveitis, and retinal vein occlusion, and consequently provides the evidences that may expand the knowledge and support the employment of surgical options.

Original languageEnglish (US)
Pages (from-to)1242-1250
Number of pages9
JournalOcular Immunology and Inflammation
Issue number8
StatePublished - Nov 17 2019


  • Diabetic retinopathy
  • macular edema
  • retinal vein occlusion
  • review
  • surgical therapy
  • uveitis
  • vitrectomy

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology


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