Surgical perspectives in peptic ulcer disease and gastritis

Tamar Lipof, David Shapiro, Robert A. Kozol

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


For much of the twentieth century, surgery was frequently the solution for peptic ulcer disease. Our understanding of the pathophysiology of ulcers paralleled the development of potent pharmaceutical therapy. As the surgical world developed parietal cell vagotomy which would minimize the complications of surgery, patients failing medical therapy became rare. Emergent surgery for complicated peptic ulcers has not declined however. The development of proton pump inhibitors and the full understanding of the impact of H pylori has led to a trend towards minimalism in surgical therapy for complicated peptic ulcer disease. In addition to the changes in patient care, these developments have had an impact on the training of surgeons. This article outlines these trends and developments.

Original languageEnglish (US)
Pages (from-to)3248-3252
Number of pages5
JournalWorld Journal of Gastroenterology
Issue number20
StatePublished - May 28 2006


  • Gastritis
  • Peptic ulcer disease
  • Perspectives

ASJC Scopus subject areas

  • Gastroenterology


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