Surgical outcomes of superior versus inferior glaucoma drainage device implantation

Amy Z. Martino, Shawn Iverson, William J. Feuer, David S. Greenfield

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Purpose: To compare the safety and intraocular pressure (IOP) lowering efficacy of initial glaucoma drainage device (GDD) implantation performed at the superior versus inferior limbus. Methods: A retrospective chart review was conducted to identify patients with glaucoma who had undergone initial Baerveldt GDD surgery at the inferior limbus for uncontrolled IOP. All eyes of patients had a minimum of 6 months of postoperative follow-up. These eyes were frequency-matched to eyes with initial Baerveldt GDD implantation performed at the superior limbus, within 5 years of age and 6 months of follow-up. Baseline demographic and clinical information, as well as preoperative and postoperative IOP, visual acuity, and number of antiglaucoma medications were extracted. Failure was defined as IOP > 21 μm Hg or not reduced by 20% below baseline on 2 consecutive follow-up visits after 3 months, IOPr5 mm Hg on 2 consecutive follow-up visits after 3 months, reoperation for glaucoma, or loss of light perception vision. Statistical methods consisted of Student t tests, w2 test, and Kaplan-Meier time to failure analysis. Results: Fifty eyes (17 inferior, 33 superior) of 43 patients were enrolled. Mean postoperative follow-up in both groups were similar (mean 26.2 ± 15.2 mo for inferior and 23.9 ± 10.43 mo for superior, P = 0.54). Trabeculectomy had been performed previously in 8/17 (47%) and 11/33 (33%) eyes (P = 0.34) with inferior and superior implants, respectively. Mean preoperative IOP (mm Hg) in the superior group (26 ± 11) was significantly higher (P = 0.02) when compared with the inferior group (21 ± 7). Success rates were similar (P > 0.05) between the inferior and superior GDD groups during the study period, with 64.7% and 75.8% classified as successful at 1-year of follow-up and 43.1% and 65.7% at 2 years of follow-up, respectively. There was no difference in cumulative proportions of eyes failing between the groups (P = 0.20, log-rank test). The mean postoperative IOP and number of antiglaucoma medications were similar (all P > 0.05) in both groups during the first 2 years of postoperative follow-up. The frequency and types of postoperative complications in both the groups were similar. The 36-month cumulative reoperation rates for IOP control were 33.8% and 9.1%, respectively, in the inferior and superior GDD groups (P = 0.04 log-rank test). Conclusions: No differences were observed in the overall success rates of initial GDD implantation performed at the superior and inferior limbus in this cohort. However, inferior GDD implantation was associated with a greater incidence of reoperation for IOP control.

Original languageEnglish (US)
Pages (from-to)32-36
Number of pages5
JournalJournal of glaucoma
Volume24
Issue number1
DOIs
StatePublished - Jan 2015

Keywords

  • Baerveldt
  • Glaucoma
  • Glaucoma drainage device
  • Inferior
  • Intraocular pressure
  • Superior

ASJC Scopus subject areas

  • Ophthalmology

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