Surgical management of large adrenal tumours: The University of Miami experience using liver transplantation techniques

Spiros G. Delis, Andreas Bakogiannis, Gaetano Ciancio, Mark Soloway

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

OBJECTIVE: To report our experience in the surgical management of patients with large adrenal masses and describe the key steps in performing radical resections, which are especially demanding where thrombi extend into the inferior vena cava (IVC). PATIENTS AND METHODS: From 2003 to 2007, 14 patients presented with large adrenal mass, and underwent surgical extirpation. In five patients thrombi extended into the IVC, causing Budd-Chiari syndrome in one. RESULTS: The median (range) patient age was 48 (40-58) years. The excision was radical with negative tumour margins in all cases. Cardiopulmonary bypass (CPB) was required in one case with adherent intra-atrial thrombus. The mean blood loss was 500 (250-1500) mL except in the patient who required CPB. Morbidity included pleural effusion (three patients) and postoperative pneumonia (two), which responded to conservative management. All patients were alive and free of disease at a median follow-up of 12 (5-42) months. CONCLUSIONS: Surgical extirpation of large adrenal masses requires technical experience to optimize outcome. Total tumour excision is the only therapeutic option in such cases and provides acceptable results in survival and quality of life.

Original languageEnglish
Pages (from-to)1394-1399
Number of pages6
JournalBJU International
Volume102
Issue number10
DOIs
StatePublished - Nov 1 2008

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Glandular and Epithelial Neoplasms
Liver Transplantation
Thrombosis
Inferior Vena Cava
Cardiopulmonary Bypass
Budd-Chiari Syndrome
Pleural Effusion
Neoplasms
Pneumonia
Quality of Life
Morbidity
Survival

Keywords

  • Adrenal gland resection
  • Adrenal gland tumour
  • Adrenalectomy
  • Vena cava thrombosis

ASJC Scopus subject areas

  • Urology

Cite this

Surgical management of large adrenal tumours : The University of Miami experience using liver transplantation techniques. / Delis, Spiros G.; Bakogiannis, Andreas; Ciancio, Gaetano; Soloway, Mark.

In: BJU International, Vol. 102, No. 10, 01.11.2008, p. 1394-1399.

Research output: Contribution to journalArticle

Delis, Spiros G. ; Bakogiannis, Andreas ; Ciancio, Gaetano ; Soloway, Mark. / Surgical management of large adrenal tumours : The University of Miami experience using liver transplantation techniques. In: BJU International. 2008 ; Vol. 102, No. 10. pp. 1394-1399.
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