Surgical Management of Anterior Chamber Migration of a Dexamethasone Intravitreal Implant

Christopher R. Stelton, Justin Townsend, Luke T. Peterson, Rahul N. Khurana, Steven Yeh

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background and Objective: Anterior chamber migration of the dexamethasone intravitreal implant (Ozurdex; Allergan, Irvine, CA) may lead to corneal edema and elevated intraocular pressure, warranting removal of the implant. Materials and Methods: A 59-year-old patient with a history of prior vitrectomy, a posterior chamber intraocular lens with a disrupted posterior capsule, and a large inferior peripheral iridectomy presented with decreased vision due to corneal edema following dexamethasone intravitreal implant injection. The authors describe their technique for implant removal, which uses standard vitreoretinal instrumentation, viscoelastic, a modified Sheets glide, and angled forceps in order to avoid fragmentation of the implant and limit iatrogenic morbidity. Results: The implant was successfully explanted. Postoperatively, the patient experienced improvement in the corneal edema, and after Descemet's stripping endothelial keratoplasty achieved a final best corrected visual acuity of 20/60 at final 12-month follow-up. Conclusion: Patients with aphakic lens status, anterior chamber intraocular lens with a disrupted posterior capsule, posterior chamber intraocular lens and a ruptured capsule, prior vitrectomy, and large peripheral iridectomies may be susceptible to migration of dexamethasone intravitreal implants into the anterior chamber.

Original languageEnglish (US)
Pages (from-to)756-759
Number of pages4
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume46
Issue number7
DOIs
StatePublished - Jul 1 2015
Externally publishedYes

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Corneal Edema
Intraocular Lenses
Anterior Chamber
Iridectomy
Dexamethasone
Capsules
Vitrectomy
Descemet Stripping Endothelial Keratoplasty
Intravitreal Injections
Intraocular Pressure
Surgical Instruments
Lenses
Visual Acuity
Morbidity

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery

Cite this

Surgical Management of Anterior Chamber Migration of a Dexamethasone Intravitreal Implant. / Stelton, Christopher R.; Townsend, Justin; Peterson, Luke T.; Khurana, Rahul N.; Yeh, Steven.

In: Ophthalmic Surgery Lasers and Imaging Retina, Vol. 46, No. 7, 01.07.2015, p. 756-759.

Research output: Contribution to journalArticle

Stelton, Christopher R. ; Townsend, Justin ; Peterson, Luke T. ; Khurana, Rahul N. ; Yeh, Steven. / Surgical Management of Anterior Chamber Migration of a Dexamethasone Intravitreal Implant. In: Ophthalmic Surgery Lasers and Imaging Retina. 2015 ; Vol. 46, No. 7. pp. 756-759.
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