Intravenous administration of synthetic human pancreatic polypeptide (hPP) with 36 amino acid residues significantly decreased immunoreactive somatostatin levels in both hepatic portal and systemic plasma in anesthetized rats. The effect of hPP on plasma somatostatin levels is acute. The results suggest that hPP may have a role in controlling somatostatin secretion from the gut and pancreas.
|Original language||English (US)|
|Number of pages||6|
|Journal||Biochemical and biophysical research communications|
|State||Published - Aug 13 1979|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology