99mTc-DTPA-galactosyl-human-serum-albumin liver scintigraphy for evaluating hepatic functional reserve before hepatectomy in a patient with indocyanine green excretory defect: Report of a case

Jun Kadono, Hizuru Kumemura, Seigo Nishida, Noboru Nakamura, Kentaro Gejima, Masayuki Nakajo, Shinsaku Tsuchimochi, Jun Matsumoto, Nobuo Hamada, Ryuzo Sakata

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

A 78-year-old woman with indocyanine green (ICG) excretory defect underwent left hepatectomy for cystadenocarcinoma. The retention rate of ICG at 15 min (ICGR15) was high, at 79.3%, despite all other liver function tests showing normal values. Conversely, 99mTc-DTPA-galactosyl-human-serum-albumin (GSA) liver scintigraphy showed a reduced accumulation of GSA in the left lateral lobe, the hepatic uptake ratio of the GSA scintigraphy was 0.96, and the arterial ketone body ratio was 1.67. Based on these results, we judged that the hepatic functional reserve of this patient was adequate for left hepatectomy, which was subsequently performed uneventfully. Histopathological examination of the resected liver showed neither fibrosis nor inflammatory cell infiltration. Thus, we consider that GSA liver scintigraphy is the best diagnostic modality for evaluating hepatic functional reserve in a patient with ICG excretory defect.

Original languageEnglish (US)
Pages (from-to)481-484
Number of pages4
JournalSurgery Today
Volume36
Issue number5
DOIs
StatePublished - May 1 2006

Keywords

  • Galactosyl-serum-albumin liver scintigraphy
  • Hepatectomy
  • Indocyanine green excretory defect

ASJC Scopus subject areas

  • Surgery

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