SU‐FF‐T‐152: Comparison Between Fixed Gantry Angle Intensity Modulated Radiotherapy and Intensity Modulated Arc Therapy for Head‐And‐Neck Cancers

C. Velasco, J. Penagaricano, E. Moros, Ivaylo B Mihaylov

Research output: Contribution to journalArticle

Abstract

Purpose: To compare the dose distributions resulting form fixed gantry angle IMRT and IMAT (dynamic arc) optimization for head‐and‐neck tumors (HN). Materials and Methods: Four (HN) cases were retrospectively investigated. Pinnacle3 (v. 8.1x) was used to generate treatment plans for an IMAT and a 9‐field IMRT delivery techniques. The targets were the planning target volume (PTV) and the lymph nodes (LN). The organs at risk (OARs) were the spinal cord (cord), the cricopharyngeus, the esophagus and the parotid glands (parotids). The IMAT and IMRT plan cross‐comparison was based on dose indices used as objectives in the optimization process. The evaluated dose indices were D95 for PTV and LN and D1 for the cord and average doses for the parotids, the cricopharyngeus and the esophagus. The standard deviations of the dose (expressed as a fraction of the prescription dose) over the PTV and the LN were also tallied. The highest priority in the optimization was given to target coverage. Results: The dose indices for the PTV and the LN differed by less than 1% and 3% respectively. A reduction in OAR dose was possible in the IMRT plans while maintaining the dose standard‐deviation below 3% (used as a dose uniformity criterion) for all targets. The IMAT plans resulted in higher dose indices/average doses to the OARs by as much as 50%. The IMAT dose standard deviation in all patients for the LN and in one patient for the PTV was greater than 3%. Conclusions: A better balance between dose uniformity and dose coverage was found in the IMRT plans. In addition the IMRT plans yielded lower doses to the OARs. We hypothesize that allowing for variable gantry speed in the IMAT optimization will result in IMAT plans which are at least as good as the fixed gantry angle IMRT plans.

Original languageEnglish (US)
Number of pages1
JournalMedical Physics
Volume36
Issue number6
DOIs
StatePublished - 2009
Externally publishedYes

Fingerprint

Intensity-Modulated Radiotherapy
Organs at Risk
Lymph Nodes
Pharyngeal Muscles
Parotid Gland
Neoplasms
Esophagus
Prescriptions
Spinal Cord

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

@article{64f1421dedc74bab8b2ca512c67f089b,
title = "SU‐FF‐T‐152: Comparison Between Fixed Gantry Angle Intensity Modulated Radiotherapy and Intensity Modulated Arc Therapy for Head‐And‐Neck Cancers",
abstract = "Purpose: To compare the dose distributions resulting form fixed gantry angle IMRT and IMAT (dynamic arc) optimization for head‐and‐neck tumors (HN). Materials and Methods: Four (HN) cases were retrospectively investigated. Pinnacle3 (v. 8.1x) was used to generate treatment plans for an IMAT and a 9‐field IMRT delivery techniques. The targets were the planning target volume (PTV) and the lymph nodes (LN). The organs at risk (OARs) were the spinal cord (cord), the cricopharyngeus, the esophagus and the parotid glands (parotids). The IMAT and IMRT plan cross‐comparison was based on dose indices used as objectives in the optimization process. The evaluated dose indices were D95 for PTV and LN and D1 for the cord and average doses for the parotids, the cricopharyngeus and the esophagus. The standard deviations of the dose (expressed as a fraction of the prescription dose) over the PTV and the LN were also tallied. The highest priority in the optimization was given to target coverage. Results: The dose indices for the PTV and the LN differed by less than 1{\%} and 3{\%} respectively. A reduction in OAR dose was possible in the IMRT plans while maintaining the dose standard‐deviation below 3{\%} (used as a dose uniformity criterion) for all targets. The IMAT plans resulted in higher dose indices/average doses to the OARs by as much as 50{\%}. The IMAT dose standard deviation in all patients for the LN and in one patient for the PTV was greater than 3{\%}. Conclusions: A better balance between dose uniformity and dose coverage was found in the IMRT plans. In addition the IMRT plans yielded lower doses to the OARs. We hypothesize that allowing for variable gantry speed in the IMAT optimization will result in IMAT plans which are at least as good as the fixed gantry angle IMRT plans.",
author = "C. Velasco and J. Penagaricano and E. Moros and Mihaylov, {Ivaylo B}",
year = "2009",
doi = "10.1118/1.3181626",
language = "English (US)",
volume = "36",
journal = "Medical Physics",
issn = "0094-2405",
publisher = "AAPM - American Association of Physicists in Medicine",
number = "6",

}

TY - JOUR

T1 - SU‐FF‐T‐152

T2 - Comparison Between Fixed Gantry Angle Intensity Modulated Radiotherapy and Intensity Modulated Arc Therapy for Head‐And‐Neck Cancers

AU - Velasco, C.

AU - Penagaricano, J.

AU - Moros, E.

AU - Mihaylov, Ivaylo B

PY - 2009

Y1 - 2009

N2 - Purpose: To compare the dose distributions resulting form fixed gantry angle IMRT and IMAT (dynamic arc) optimization for head‐and‐neck tumors (HN). Materials and Methods: Four (HN) cases were retrospectively investigated. Pinnacle3 (v. 8.1x) was used to generate treatment plans for an IMAT and a 9‐field IMRT delivery techniques. The targets were the planning target volume (PTV) and the lymph nodes (LN). The organs at risk (OARs) were the spinal cord (cord), the cricopharyngeus, the esophagus and the parotid glands (parotids). The IMAT and IMRT plan cross‐comparison was based on dose indices used as objectives in the optimization process. The evaluated dose indices were D95 for PTV and LN and D1 for the cord and average doses for the parotids, the cricopharyngeus and the esophagus. The standard deviations of the dose (expressed as a fraction of the prescription dose) over the PTV and the LN were also tallied. The highest priority in the optimization was given to target coverage. Results: The dose indices for the PTV and the LN differed by less than 1% and 3% respectively. A reduction in OAR dose was possible in the IMRT plans while maintaining the dose standard‐deviation below 3% (used as a dose uniformity criterion) for all targets. The IMAT plans resulted in higher dose indices/average doses to the OARs by as much as 50%. The IMAT dose standard deviation in all patients for the LN and in one patient for the PTV was greater than 3%. Conclusions: A better balance between dose uniformity and dose coverage was found in the IMRT plans. In addition the IMRT plans yielded lower doses to the OARs. We hypothesize that allowing for variable gantry speed in the IMAT optimization will result in IMAT plans which are at least as good as the fixed gantry angle IMRT plans.

AB - Purpose: To compare the dose distributions resulting form fixed gantry angle IMRT and IMAT (dynamic arc) optimization for head‐and‐neck tumors (HN). Materials and Methods: Four (HN) cases were retrospectively investigated. Pinnacle3 (v. 8.1x) was used to generate treatment plans for an IMAT and a 9‐field IMRT delivery techniques. The targets were the planning target volume (PTV) and the lymph nodes (LN). The organs at risk (OARs) were the spinal cord (cord), the cricopharyngeus, the esophagus and the parotid glands (parotids). The IMAT and IMRT plan cross‐comparison was based on dose indices used as objectives in the optimization process. The evaluated dose indices were D95 for PTV and LN and D1 for the cord and average doses for the parotids, the cricopharyngeus and the esophagus. The standard deviations of the dose (expressed as a fraction of the prescription dose) over the PTV and the LN were also tallied. The highest priority in the optimization was given to target coverage. Results: The dose indices for the PTV and the LN differed by less than 1% and 3% respectively. A reduction in OAR dose was possible in the IMRT plans while maintaining the dose standard‐deviation below 3% (used as a dose uniformity criterion) for all targets. The IMAT plans resulted in higher dose indices/average doses to the OARs by as much as 50%. The IMAT dose standard deviation in all patients for the LN and in one patient for the PTV was greater than 3%. Conclusions: A better balance between dose uniformity and dose coverage was found in the IMRT plans. In addition the IMRT plans yielded lower doses to the OARs. We hypothesize that allowing for variable gantry speed in the IMAT optimization will result in IMAT plans which are at least as good as the fixed gantry angle IMRT plans.

UR - http://www.scopus.com/inward/record.url?scp=85024814545&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85024814545&partnerID=8YFLogxK

U2 - 10.1118/1.3181626

DO - 10.1118/1.3181626

M3 - Article

AN - SCOPUS:85024814545

VL - 36

JO - Medical Physics

JF - Medical Physics

SN - 0094-2405

IS - 6

ER -