Sudden Cardiac Death: Interface Between Pathophysiology and Epidemiology

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


The population incidence of sudden cardiac arrest (SCA) and sudden cardiac death have not changed appreciably during the decades of improvement in general outcomes from cardiovascular diseases, but the age, clinical circumstances, and pathophysiologic mechanisms have. The epidemiology and pathophysiology of SCA are linked, in that mechanisms of SCA can be modeled based on substrate and expression characteristics. The goal for the future is to expand pathophysiologic and epidemiologic interactions to achieve strong individual risk prediction, to complement the limits of application of population risk data to individuals.

Original languageEnglish (US)
Pages (from-to)515-524
Number of pages10
JournalCardiac Electrophysiology Clinics
Issue number4
StatePublished - Dec 2017


  • Asystole
  • Cardiac arrest
  • Coronary heart disease
  • Epidemiology
  • Population risk
  • Pulseless electrical activity
  • Sudden cardiac death
  • Ventricular tachyarrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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