Abstract
An 18-yr-old woman with cystic fibrosis who received a double-lung transplant developed a severe episode of acute lung rejection. Bronchoalveolar lavage and transbronchial biopsy were used to establish the diagnosis. The rejection was refractory to administration of high-dose pulse steroids. OKT3 therapy was successfully used to reverse this episode. This is the first case report of a steroid-resistant double-lung allograft rejection successfully treated with OKT3.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 224-226 |
| Number of pages | 3 |
| Journal | American Review of Respiratory Disease |
| Volume | 144 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1991 |
| Externally published | Yes |
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
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Cite this
Shennib, H., Mercado, M., Nguyen, D., Ernst, P., Lebel, F., O'Donovan, M., Fraser, R., Tchervenkov, C., Morin, J. F., & Mulder, D. (1991). Successful treatment of steroid-resistant double-lung allograft rejection with Orthoclone® OKT3. American Review of Respiratory Disease, 144(1), 224-226. https://doi.org/10.1164/ajrccm/144.1.224