Successful Treatment of Disseminated Disease Due to Highly Resistant Aspergillus calidoustus with a Novel Antifungal Therapy

Jose F. Camargo; Raed Jabr; Anthony D. Anderson; Lazaros Lekakis; Meilin Diaz-Paez; Laurence M. Briski; Mohammed Raja; Michele I. Morris; Krishna V. Komanduri; Denise Pereira

doi:10.1128/aac.02206-21

Successful Treatment of Disseminated Disease Due to Highly Resistant Aspergillus calidoustus with a Novel Antifungal Therapy

Jose F. Camargo, Raed Jabr, Anthony D. Anderson, Lazaros Lekakis, Meilin Diaz-Paez, Laurence M. Briski, Mohammed Raja, Michele I. Morris, Krishna V. Komanduri, Denise Pereira

Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Invasive aspergillosis is the most common invasive mold infection following a hematopoietic cell transplant. Widespread use of antifungal prophylaxis has led to the increasing incidence of cryptic Aspergillus species. Aspergillus calidoustus is one of those emerging species and is notorious for multidrug resistance to antifungals. Here, we report a case of disseminated A. calidoustus infection in a hematopoietic stem cell transplant recipient who was successfully treated with combination therapy that included a novel antifungal.

Original language	English (US)
Article number	e02206-21
Journal	Antimicrobial agents and chemotherapy
Volume	66
Issue number	3 March
DOIs	https://doi.org/10.1128/aac.02206-21
State	Published - Mar 2022

Keywords

APX001
Aspergillus calidoustus
hematopoietic cell transplant

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/aac.02206-21

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Camargo, J. F., Jabr, R., Anderson, A. D., Lekakis, L., Diaz-Paez, M., Briski, L. M., Raja, M., Morris, M. I., Komanduri, K. V., & Pereira, D. (2022). Successful Treatment of Disseminated Disease Due to Highly Resistant Aspergillus calidoustus with a Novel Antifungal Therapy. Antimicrobial agents and chemotherapy, 66(3 March), [e02206-21]. https://doi.org/10.1128/aac.02206-21

Successful Treatment of Disseminated Disease Due to Highly Resistant Aspergillus calidoustus with a Novel Antifungal Therapy. / Camargo, Jose F.; Jabr, Raed; Anderson, Anthony D.; Lekakis, Lazaros; Diaz-Paez, Meilin; Briski, Laurence M.; Raja, Mohammed; Morris, Michele I.; Komanduri, Krishna V.; Pereira, Denise.

In: Antimicrobial agents and chemotherapy, Vol. 66, No. 3 March, e02206-21, 03.2022.

Research output: Contribution to journal › Article › peer-review

Camargo, Jose F. ; Jabr, Raed ; Anderson, Anthony D. ; Lekakis, Lazaros ; Diaz-Paez, Meilin ; Briski, Laurence M. ; Raja, Mohammed ; Morris, Michele I. ; Komanduri, Krishna V. ; Pereira, Denise. / Successful Treatment of Disseminated Disease Due to Highly Resistant Aspergillus calidoustus with a Novel Antifungal Therapy. In: Antimicrobial agents and chemotherapy. 2022 ; Vol. 66, No. 3 March.

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Successful Treatment of Disseminated Disease Due to Highly Resistant Aspergillus calidoustus with a Novel Antifungal Therapy

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Keywords

ASJC Scopus subject areas

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