Successful ICU Care of a 14-Year-Old With Total Artificial Circulation Using Two Ventricular Assist Devices for 118 Days

Richard B. Silverman, Sean M. Quinn

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Within the first year following orthotopic heart transplantation, the patient is at risk of graft failure, rejection, and infection. Late mortality is often due to allograph vasculopathy. Most of the patients with primary graft failure will usually recover with temporary mechanical ventricular assist support; however, on occasion the patient must be retransplanted. For the patient who suffers primary graft failure necessitating explanation and bridging until a new suitable graft is found, there are several total artificial heart options. However, in the pediatric population these options are limited. The authors' surgical colleagues were able to fashion a paracorporeal total artificial heart constructed with 2 ventricular assist devices. In this case report, the authors discuss a pediatric patient who had to be explanted and supported for an extended amount of time. This article describes the incidence of cardiomyopathy in juvenile rheumatoid arthritis patients, the choice of extracorporeal membrane oxygenation/extracorporeal complete life support versus ventricular assist devices for support, the major causes of primary graft failure, and the authors' experience in caring for an adolescent with such a device for a protracted length of time (118 days).

Original languageEnglish (US)
Pages (from-to)240-246
Number of pages7
JournalICU Director
Issue number5
StatePublished - Sep 2012


  • adolescent
  • heart failure
  • heart transplantation
  • intensive care unit
  • systemic juvenile rheumatic arthritis
  • Thoratec
  • ventricular assist device

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Management Science and Operations Research
  • Critical Care


Dive into the research topics of 'Successful ICU Care of a 14-Year-Old With Total Artificial Circulation Using Two Ventricular Assist Devices for 118 Days'. Together they form a unique fingerprint.

Cite this