Successful extracorporeal circulatory support after aortic reimplantation of anomalous left coronary artery

V. Alexi-Meskishvili, R. Hetzer, Y. Weng, Matthias Loebe, P. E. Lange, K. Ishino

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The development of severe heart failure is the main cause of postoperative mortality after the surgical treatment of anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA). Two patients with ALCAPA who developed low cardiac output and could not be weaned from cardiopulmonary bypass (CPB) after aortic reimplantation of the the anomalous left coronary artery were successfully treated with a centrifugal left ventricular assist device (LVAD) and extracorporeal membrane oxygenation (ECMO). The circulation of a 10-month-old infant with severe left ventricular dysfunction was supported 192 h postoperatively with a LVAD and a 9-year-old boy with severe right ventricular failure received ECMO support for 99 h following surgery. Both patients survived and, 4 and 9 months after surgery, are asymptomatic and have normal ventricular function. If CPB (up to 3 h) is not effective in improving ventricular function after surgery for ALCAPA, ECMO or LVAD must be used since myocardial recovery in these patients can occur only after prolonged extracorporeal circulatory support.

Original languageEnglish (US)
Pages (from-to)533-536
Number of pages4
JournalEuropean Journal of Cardio-thoracic Surgery
Volume8
Issue number10
StatePublished - 1994
Externally publishedYes

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Replantation
Extracorporeal Membrane Oxygenation
Heart-Assist Devices
Coronary Vessels
Pulmonary Artery
Ventricular Function
Cardiopulmonary Bypass
Low Cardiac Output
Left Ventricular Dysfunction
Heart Failure
Mortality
Therapeutics

Keywords

  • Assisted circulation
  • Coronary malformations
  • Extracorporeal membrane oxygenation
  • Myocardial recovery

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

Successful extracorporeal circulatory support after aortic reimplantation of anomalous left coronary artery. / Alexi-Meskishvili, V.; Hetzer, R.; Weng, Y.; Loebe, Matthias; Lange, P. E.; Ishino, K.

In: European Journal of Cardio-thoracic Surgery, Vol. 8, No. 10, 1994, p. 533-536.

Research output: Contribution to journalArticle

Alexi-Meskishvili, V. ; Hetzer, R. ; Weng, Y. ; Loebe, Matthias ; Lange, P. E. ; Ishino, K. / Successful extracorporeal circulatory support after aortic reimplantation of anomalous left coronary artery. In: European Journal of Cardio-thoracic Surgery. 1994 ; Vol. 8, No. 10. pp. 533-536.
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