Successful epilepsy surgery in frontal lobe epilepsy with startle seizures: A SEEG study

Ana Ciurea, Irina Popa, Mihai Dragos Maliia, Nagy Csilla-Johanna, Andrei Barborica, Cristian Donos, Jean Ciurea, Ioan Opris, Ioana Mindruta

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Pre-surgical assessment and surgical management of frontal epilepsy with normal MRI is often challenging. We present a case of a 33-year-old, right-handed, educated male. During childhood, his seizures presented with mandibular myoclonus and no particular trigger. As a young adult, he developed seizures with a startle component, triggered by unexpected noises. During his ictal episodes, he felt fear and grimaced with sudden head flexion and tonic axial posturing. Similar seizures also occurred without startle. Neuropsychological assessment showed executive dysfunction and verbal memory deficit. The cerebral MRI was normal. Electro-clinical reasoning, investigations performed, the results obtained and follow-up are discussed in detail.

Original languageEnglish (US)
Pages (from-to)363-371
Number of pages9
JournalEpileptic Disorders
Issue number4
StatePublished - Dec 2015
Externally publishedYes


  • Focal cortical dysplasia
  • Mesial fronto-parietal network
  • SEEG
  • Startle epilepsy

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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