Subretinal aspiration biopsy of ocular lymphoma

T. A. Ciulla, R. D. Pesavento, S. Yoo

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


PURPOSE: Large-cell lymphoma can be difficult to diagnose because vitreous biopsies may fail to disclose neoplastic cells. METHODS: We report one such case in which diagnosis was confirmed by subretinal aspiration of yellow-white infiltrates using a pars plana approach. RESULTS: A 67-year-old woman with recurrent bilateral uveitis was diagnosed with large-cell lymphoma by subretinal aspiration of yellow-white infiltrates after two vitreous biopsies and a concurrent retinal biopsy failed to confirm the diagnosis. CONCLUSION: When the suspicion of intraocular lymphoma remains high despite previous negative vitreous biopsies, retinal biopsy and aspiration biopsy of subretinal lesions may enhance the diagnostic yield.

Original languageEnglish (US)
Pages (from-to)420-422
Number of pages3
JournalAmerican journal of ophthalmology
Issue number3
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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