Sepsis due to Pseudomonas aeruginosa continues to be an important source of morbidity and mortality in hospitalized patients. Early recognition of this condition is of paramount importance in choosing specific therapy at the earliest possible moment. We present three cases in which P aeruginosa bacteremia was manifested by subcutaneous nodules. Although such lesions have been reported before, we place new emphasis on the uniqueness of this lesion to P aeruginosa, the feasibility of visualizing the organism and culturing it from biopsies of the lesions, and the possibility of choosing appropriate therapy early through recognition.
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