Abstract
Objective: To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods: Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988-1994) and its linked mortality file (with follow-up death up to 2000) were used. Results: Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48-0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion: Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.
| Original language | English |
|---|---|
| Pages (from-to) | 289-291 |
| Number of pages | 3 |
| Journal | Journal of Diabetes and its Complications |
| Volume | 25 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 1 2011 |
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Keywords
- Diabetes
- Glycemic control
- Mortality
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
- Internal Medicine
Cite this
Strict glycemic control and mortality risk among US adults with type 2 diabetes. / Davila, Evelyn P.; Florez, Hermes J; Trepka, Mary Jo; Fleming, Lora E.; Niyonsenga, Theophile; Lee, David J; Parkash, Jai.
In: Journal of Diabetes and its Complications, Vol. 25, No. 5, 01.09.2011, p. 289-291.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Strict glycemic control and mortality risk among US adults with type 2 diabetes
AU - Davila, Evelyn P.
AU - Florez, Hermes J
AU - Trepka, Mary Jo
AU - Fleming, Lora E.
AU - Niyonsenga, Theophile
AU - Lee, David J
AU - Parkash, Jai
PY - 2011/9/1
Y1 - 2011/9/1
N2 - Objective: To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods: Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988-1994) and its linked mortality file (with follow-up death up to 2000) were used. Results: Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48-0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion: Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.
AB - Objective: To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods: Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988-1994) and its linked mortality file (with follow-up death up to 2000) were used. Results: Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48-0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion: Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.
KW - Diabetes
KW - Glycemic control
KW - Mortality
UR - http://www.scopus.com/inward/record.url?scp=80052730834&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052730834&partnerID=8YFLogxK
U2 - 10.1016/j.jdiacomp.2011.03.004
DO - 10.1016/j.jdiacomp.2011.03.004
M3 - Article
C2 - 21658973
AN - SCOPUS:80052730834
VL - 25
SP - 289
EP - 291
JO - Journal of Diabetes and its Complications
JF - Journal of Diabetes and its Complications
SN - 1056-8727
IS - 5
ER -