Strict glycemic control and mortality risk among US adults with type 2 diabetes

Evelyn P. Davila; Hermes Florez; Mary Jo Trepka; Lora E. Fleming; Theophile Niyonsenga; David J. Lee; Jai Parkash

doi:10.1016/j.jdiacomp.2011.03.004

Strict glycemic control and mortality risk among US adults with type 2 diabetes

Evelyn P. Davila, Hermes Florez, Mary Jo Trepka, Lora E. Fleming, Theophile Niyonsenga, David J. Lee, Jai Parkash

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Objective: To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods: Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988-1994) and its linked mortality file (with follow-up death up to 2000) were used. Results: Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48-0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion: Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.

Original language	English (US)
Pages (from-to)	289-291
Number of pages	3
Journal	Journal of Diabetes and Its Complications
Volume	25
Issue number	5
DOIs	https://doi.org/10.1016/j.jdiacomp.2011.03.004
State	Published - Sep 2011

Keywords

Diabetes
Glycemic control
Mortality

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism
Internal Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jdiacomp.2011.03.004

Cite this

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title = "Strict glycemic control and mortality risk among US adults with type 2 diabetes",

abstract = "Objective: To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods: Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988-1994) and its linked mortality file (with follow-up death up to 2000) were used. Results: Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48-0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion: Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.",

keywords = "Diabetes, Glycemic control, Mortality",

author = "Davila, {Evelyn P.} and Hermes Florez and Trepka, {Mary Jo} and Fleming, {Lora E.} and Theophile Niyonsenga and Lee, {David J.} and Jai Parkash",

note = "Funding Information: This research was in part supported by the National Institute on Occupational Safety and Health (R01-0H03915). ",

year = "2011",

month = sep,

doi = "10.1016/j.jdiacomp.2011.03.004",

language = "English (US)",

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T1 - Strict glycemic control and mortality risk among US adults with type 2 diabetes

AU - Davila, Evelyn P.

AU - Florez, Hermes

AU - Trepka, Mary Jo

AU - Fleming, Lora E.

AU - Niyonsenga, Theophile

AU - Lee, David J.

AU - Parkash, Jai

N1 - Funding Information: This research was in part supported by the National Institute on Occupational Safety and Health (R01-0H03915).

PY - 2011/9

Y1 - 2011/9

N2 - Objective: To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods: Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988-1994) and its linked mortality file (with follow-up death up to 2000) were used. Results: Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48-0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion: Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.

AB - Objective: To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods: Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988-1994) and its linked mortality file (with follow-up death up to 2000) were used. Results: Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48-0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion: Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.

KW - Diabetes

KW - Glycemic control

KW - Mortality

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Strict glycemic control and mortality risk among US adults with type 2 diabetes

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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