Strict glycemic control and mortality risk among US adults with type 2 diabetes

Evelyn P. Davila, Hermes Florez, Mary Jo Trepka, Lora E. Fleming, Theophile Niyonsenga, David J. Lee, Jai Parkash

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Objective: To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods: Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988-1994) and its linked mortality file (with follow-up death up to 2000) were used. Results: Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48-0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion: Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.

Original languageEnglish (US)
Pages (from-to)289-291
Number of pages3
JournalJournal of Diabetes and Its Complications
Issue number5
StatePublished - Sep 2011


  • Diabetes
  • Glycemic control
  • Mortality

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine


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