Stress Management, Depression, and Immune Status in Lower-Income Racial/Ethnic Minority Women Co-infected with HIV and HPV

Corina R. Lopez, Michael H. Antoni, Julia Seay, Jonelle Potter, Mary J. O'Sullivan, Mary Ann Fletcher, Deirdre Pereira, Nicole Whitehead

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The stress of co-infection with human immunodeficiency virus (HIV) and human papillomavirus (HPV), in race/ethnic minority women, may increase depression and immune decrements. Compromised immunity in HIV+ HPV+ women may increase the odds of cervical dysplasia. Thus, we tested the efficacy of a 10-week cognitive behavioral stress management (CBSM) group intervention and hypothesized that CBSM would decrease depression and improve immune status (CD4+ T-cells, natural killer [NK] cells). HIV+ HPV+ women (n=71) completed the Beck Depression Inventory and provided blood samples, were randomized to CBSM or a control condition, and were re-assessed post-intervention. Women in CBSM revealed less depression, greater NK cells, and marginally greater CD4+ T-cells post-intervention vs. controls. Stress management may improve mood and immunity in HIV+ HPV+ lower-income minority women.

Original languageEnglish (US)
Pages (from-to)37-57
Number of pages21
JournalJournal of Applied Biobehavioral Research
Volume18
Issue number1
DOIs
StatePublished - Mar 1 2013

ASJC Scopus subject areas

  • Cultural Studies
  • Experimental and Cognitive Psychology
  • Clinical Psychology
  • Social Sciences (miscellaneous)

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