Stress management and immune system reconstitution in symptomatic HIV-infected gay men over time: Effects on transitional naive T cells (CD4 +CD45RA+CD29+)

Michael H. Antoni, Dean G. Cruess, Nancy Klimas, Kevin Maher, Stacy Cruess, Mahendra Kumar, Susan Lutgendorf, Gail Ironson, Neil Schneiderman, Mary Ann Fletcher

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Objective: Changes in immunologic status were evaluated in 25 HIV-infected men randomly assigned to a 10-week stress management intervention or a wait-list control condition. Method: The authors monitored changes in number of transitional naive T cells (CD4+CD45RA+CD29+) over 6-12 months after the completion of the intervention. Results: Men receiving stress management had higher CD4+ CD45RA +CD29+ cell counts at follow-up than did the control subjects. This difference was independent of initial number of naive T cells and HIV virus load. Conclusions: Stress management is associated with immunologic reconstitution in HIV-positive gay men.

Original languageEnglish (US)
Pages (from-to)143-145
Number of pages3
JournalAmerican Journal of Psychiatry
Issue number1
StatePublished - Jan 1 2002


ASJC Scopus subject areas

  • Psychiatry and Mental health

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