Stress, coping, and circadian disruption among women awaiting breast cancer surgery

Eric Dedert, Elizabeth Lush, Anees Chagpar, Firdaus Dhabhar, Suzanne C. Segerstrom, David Spiegel, Ehab Dayyat, Meagan Daup, Kelly McMasters, Sandra E. Sephton

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Background Psychological distress and coping related to a breast cancer diagnosis can profoundly affect psychological adjustment, possibly resulting in the disruption of circadian rest/ activity and cortisol rhythms, which are prognostic for early mortality inmetastatic colorectal and breast cancers, respectively. Purpose This study aims to explore the relationships of cancer-specific distress and avoidant coping with rest/activity and cortisol rhythmdisruption in the period between diagnosis and breast cancer surgery. Methods Fifty-seven presurgical breast cancer patients provided daily self-reports of cancer-specific distress and avoidant coping as well as actigraphic and salivary cortisol data. Results Distress and avoidant coping were related to rest/ activity rhythm disruption (daytime sedentariness, inconsistent rhythms). Patients with disrupted rest/activity cycles had flattened diurnal cortisol rhythms. Conclusions Maladaptive psychological responses to breast cancer diagnosis were associated with disruption of circadian rest/activity rhythms. Given that circadian cycles regulate tumor growth, we need greater understanding of possible psychosocial effects in cancer-related circadian disruption.

Original languageEnglish (US)
Pages (from-to)10-20
Number of pages11
JournalAnnals of Behavioral Medicine
Volume44
Issue number1
DOIs
StatePublished - Aug 1 2012
Externally publishedYes

Fingerprint

Hydrocortisone
Breast Neoplasms
Neoplasms
Psychology
Activity Cycles
Circadian Rhythm
Self Report
Colorectal Neoplasms
Mortality
Growth

Keywords

  • Actigraphy
  • Breast cancer
  • Circadian rhythm
  • Cortisol
  • Rest/activity
  • Sleep

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health

Cite this

Dedert, E., Lush, E., Chagpar, A., Dhabhar, F., Segerstrom, S. C., Spiegel, D., ... Sephton, S. E. (2012). Stress, coping, and circadian disruption among women awaiting breast cancer surgery. Annals of Behavioral Medicine, 44(1), 10-20. https://doi.org/10.1007/s12160-012-9352-y

Stress, coping, and circadian disruption among women awaiting breast cancer surgery. / Dedert, Eric; Lush, Elizabeth; Chagpar, Anees; Dhabhar, Firdaus; Segerstrom, Suzanne C.; Spiegel, David; Dayyat, Ehab; Daup, Meagan; McMasters, Kelly; Sephton, Sandra E.

In: Annals of Behavioral Medicine, Vol. 44, No. 1, 01.08.2012, p. 10-20.

Research output: Contribution to journalArticle

Dedert, E, Lush, E, Chagpar, A, Dhabhar, F, Segerstrom, SC, Spiegel, D, Dayyat, E, Daup, M, McMasters, K & Sephton, SE 2012, 'Stress, coping, and circadian disruption among women awaiting breast cancer surgery', Annals of Behavioral Medicine, vol. 44, no. 1, pp. 10-20. https://doi.org/10.1007/s12160-012-9352-y
Dedert, Eric ; Lush, Elizabeth ; Chagpar, Anees ; Dhabhar, Firdaus ; Segerstrom, Suzanne C. ; Spiegel, David ; Dayyat, Ehab ; Daup, Meagan ; McMasters, Kelly ; Sephton, Sandra E. / Stress, coping, and circadian disruption among women awaiting breast cancer surgery. In: Annals of Behavioral Medicine. 2012 ; Vol. 44, No. 1. pp. 10-20.
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