Stress and the Impact of Personalized Medicine

Charles F. Gillespie, Elisabeth B. Binder, Paul E. Holtzheimer, Charles B. Nemeroff

Research output: Chapter in Book/Report/Conference proceedingChapter


This report summarizes a number of the epigenetic influence on the development and treatment of anxiety and mood disorders. The focus taken here is on the impact of stress and stressors on the endocrine axis and their effects on the anxiety and mood disorders. There have been a number of interesting leads as to what the relevant important genetic components may be however none have been studied sufficiently to be used as Personalized Medicine markers for anxiety or depression.

Original languageEnglish (US)
Title of host publicationIntegrative Neuroscience and Personalized Medicine
PublisherOxford University Press
ISBN (Electronic)9780199863495
ISBN (Print)9780195393804
StatePublished - Jan 1 2011


  • Abuse
  • Anxiety
  • Brain imaging
  • Depression
  • Genes
  • Ghypothalamic-pituitary-adrenal axis
  • Neuroendocrine
  • SNPs
  • Stress
  • Stressors

ASJC Scopus subject areas

  • Neuroscience(all)


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