Stress and health: Psychological, behavioral, and biological determinants

Research output: Contribution to journalReview articlepeer-review

745 Scopus citations


Stressors have a major influence upon mood, our sense of well-being, behavior, and health. Acute stress responses in young, healthy individuals may be adaptive and typically do not impose a health burden. However, if the threat is unremitting, particularly in older or unhealthy individuals, the long-term effects of stressors can damage health. The relationship between psychosocial stressors and disease is affected by the nature, number, and persistence of the stressors as well as by the individual's biological vulnerability (i.e., genetics, constitutional factors), psychosocial resources, and learned patterns of coping. Psychosocial interventions have proven useful for treating stress-related disorders and may influence the course of chronic diseases.

Original languageEnglish (US)
Pages (from-to)607-628
Number of pages22
JournalAnnual Review of Clinical Psychology
StatePublished - 2005


  • Homeostasis
  • Host vulnerability-stressor interactions
  • Psychosocial interventions
  • Psychosocial stressors
  • Stress responses

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology


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