Abstract
A considerable body of evidence, reviewed in this chapter, suggests that psychosocial factors play an important role in progression of HIV infection, its morbidity and mortality. Psychosocial influences relating to faster disease progression include life-event stress, sustained depression, denial/avoidance coping, concealment of gay identity (unless one is rejection-sensitive), and negative expectancies. Conversely, protective psychosocial factors include active coping, finding new meaning, and stress management. In studying long survivors of HIV/AIDS, our group has found protective effects on health of life involvement, collaborative relationship with doctor, emotional expression, depression (conversely), and perceived stress (conversely). Reviewed and discussed are psychoneuroimmunological pathways by which immune and neuroendocrine mechanisms might link psychosocial factors with health and long survival. Finally, biological factors are also a major determinant of disease progression and include genetics and age of the host, viral strain and virulence, medication and several immune response factors on which psychosocial influences could impact.
| Original language | English |
|---|---|
| Pages (from-to) | 615-633 |
| Number of pages | 19 |
| Journal | Bailliere's Best Practice and Research in Clinical Endocrinology and Metabolism |
| Volume | 13 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 1 1999 |
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Keywords
- AIDS
- Disease progression
- HIV
- HIV long-term survivors
- Immunity
- Life-change events
- PNI
- Psychology and HIV
- Psychoneuroimmunology
- Stress
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
Stress and coping : The psychoneuroimmunology of HIV/AIDS. / Balbin, Elizabeth G.; Ironson, Gail; Solomon, George F.
In: Bailliere's Best Practice and Research in Clinical Endocrinology and Metabolism, Vol. 13, No. 4, 01.12.1999, p. 615-633.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Stress and coping
T2 - The psychoneuroimmunology of HIV/AIDS
AU - Balbin, Elizabeth G.
AU - Ironson, Gail
AU - Solomon, George F.
PY - 1999/12/1
Y1 - 1999/12/1
N2 - A considerable body of evidence, reviewed in this chapter, suggests that psychosocial factors play an important role in progression of HIV infection, its morbidity and mortality. Psychosocial influences relating to faster disease progression include life-event stress, sustained depression, denial/avoidance coping, concealment of gay identity (unless one is rejection-sensitive), and negative expectancies. Conversely, protective psychosocial factors include active coping, finding new meaning, and stress management. In studying long survivors of HIV/AIDS, our group has found protective effects on health of life involvement, collaborative relationship with doctor, emotional expression, depression (conversely), and perceived stress (conversely). Reviewed and discussed are psychoneuroimmunological pathways by which immune and neuroendocrine mechanisms might link psychosocial factors with health and long survival. Finally, biological factors are also a major determinant of disease progression and include genetics and age of the host, viral strain and virulence, medication and several immune response factors on which psychosocial influences could impact.
AB - A considerable body of evidence, reviewed in this chapter, suggests that psychosocial factors play an important role in progression of HIV infection, its morbidity and mortality. Psychosocial influences relating to faster disease progression include life-event stress, sustained depression, denial/avoidance coping, concealment of gay identity (unless one is rejection-sensitive), and negative expectancies. Conversely, protective psychosocial factors include active coping, finding new meaning, and stress management. In studying long survivors of HIV/AIDS, our group has found protective effects on health of life involvement, collaborative relationship with doctor, emotional expression, depression (conversely), and perceived stress (conversely). Reviewed and discussed are psychoneuroimmunological pathways by which immune and neuroendocrine mechanisms might link psychosocial factors with health and long survival. Finally, biological factors are also a major determinant of disease progression and include genetics and age of the host, viral strain and virulence, medication and several immune response factors on which psychosocial influences could impact.
KW - AIDS
KW - Disease progression
KW - HIV
KW - HIV long-term survivors
KW - Immunity
KW - Life-change events
KW - PNI
KW - Psychology and HIV
KW - Psychoneuroimmunology
KW - Stress
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UR - http://www.scopus.com/inward/citedby.url?scp=0033508772&partnerID=8YFLogxK
U2 - 10.1053/beem.1999.0047
DO - 10.1053/beem.1999.0047
M3 - Article
VL - 13
SP - 615
EP - 633
JO - Best Practice and Research in Clinical Endocrinology and Metabolism
JF - Best Practice and Research in Clinical Endocrinology and Metabolism
SN - 1521-690X
IS - 4
ER -