TY - JOUR
T1 - Stimulus generalization and transfer of training in rabbits conditioned to electrical stimulation of lateral geniculate nucleus
AU - Swadlow, Harvey A.
AU - Schneiderman, Neil
N1 - Funding Information:
The purpose of assessing generalization gradients to brain stimulation under the above conditions was to obtain an index of the amount and types of information which can be analyzed or discriminated by the neuronal system under the electrode tip. Examination of the LGN in the present study was chosen for several reasons. First, previous classical discrimination conditioning experiments in rabbits have shown 1Supported by research grant GB7944 from the National Science Foundation and by NICHHD training grant 00187 in Quantitative Organismic Biology to the Laboratory for Quantitative Biology. We thank Daniel B. Cruse for advice and Gary Carson for technical assistance. INIMH Predoctoral Fellow. Now an NIH Postdoctoral Fellow at the Center for Brain Research, University of Rochester.
PY - 1970/8
Y1 - 1970/8
N2 - Rabbits were classically conditioned by pairing electrical stimulation of the dorsal lateral geniculate nucleus (LGN) with peripheral electric shock as the unconditioned stimulus. In Experiment 1 generalization and transfer of training between contralateral LGN were examined. In Experiment 2 frequency generalization gradients were examined with total stimulus energy (TSE) either varied or kept constant. The chief findings of Experiment 1 were that (a) reliable eyeblink and heart rate conditioning were observed, and (b) transfer of training, but not stimulus generalization occurred between LGN. This transfer was specifically due to the previous conditioning. In Experiment 2 response frequency of unconditioned eye openings to LGN stimulation varied as a function of stimulus frequency. In contrast, the highest response frequency for conditioned eyelid closings during generalization testing occurred at the stimulus frequency used during training provided that TSE was kept constant; some generalization occurred to higher and lower stimulus frequencies. When frequency was varied without keeping TSE constant, the highest response rates occurred at stimulus frequencies higher than the training stimulus.
AB - Rabbits were classically conditioned by pairing electrical stimulation of the dorsal lateral geniculate nucleus (LGN) with peripheral electric shock as the unconditioned stimulus. In Experiment 1 generalization and transfer of training between contralateral LGN were examined. In Experiment 2 frequency generalization gradients were examined with total stimulus energy (TSE) either varied or kept constant. The chief findings of Experiment 1 were that (a) reliable eyeblink and heart rate conditioning were observed, and (b) transfer of training, but not stimulus generalization occurred between LGN. This transfer was specifically due to the previous conditioning. In Experiment 2 response frequency of unconditioned eye openings to LGN stimulation varied as a function of stimulus frequency. In contrast, the highest response frequency for conditioned eyelid closings during generalization testing occurred at the stimulus frequency used during training provided that TSE was kept constant; some generalization occurred to higher and lower stimulus frequencies. When frequency was varied without keeping TSE constant, the highest response rates occurred at stimulus frequencies higher than the training stimulus.
KW - Brain stimulation
KW - Classical conditioning
KW - Frequency generalization
KW - Lateral geniculate nucleus
KW - Rabbits
KW - Stimulus generalization
KW - Transfer of training
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U2 - 10.1016/0031-9384(70)90169-1
DO - 10.1016/0031-9384(70)90169-1
M3 - Article
C2 - 5522502
AN - SCOPUS:0014826337
VL - 5
SP - 841
EP - 847
JO - Physiology and Behavior
JF - Physiology and Behavior
SN - 0031-9384
IS - 8
ER -