Steroid hormone receptors and melanoma

J. P. Neifeld, M. E. Lippman

Research output: Contribution to journalReview article

59 Scopus citations

Abstract

Although several tentative conclusions may be tendered regarding steroid hormone receptors and melanoma, it must be remembered that only a small number of patients have been investigated and that these statements may change as more data become available. Retrospective studies suggest a small subset of patients with melanoma may have tumors responsive to steroid hormones. The data from several centers suggest that a small percentage of patients have tumors that contain specific high affinity, limited capacity binding for steroid hormones. The presence (or absence) of steroid hormone binding activity in melanoma has not been shown to correlate with in vivo (and possibly in vitro) responses to endocrine manipulation.

Original languageEnglish (US)
Pages (from-to)379-381
Number of pages3
JournalJournal of Investigative Dermatology
Volume74
Issue number6
DOIs
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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