Stability of mood states and biochemistry across pregnancy

Tiffany M Field, Maria Hernandez-Reif, Miguel A Diego, Saul Schanberg, Cynthia Kuhn

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Four hundred and thirty pregnant women were recruited during their second trimester of pregnancy (M = 20 weeks). They were designated depressed (N = 172) or nondepressed (N = 258) on the Structured Clinical Interview of Depression (SCID) and the Center for Epidemiological Studies Depression scale (CES-D). They were given a second assessment when they were approximately 32 weeks gestational age. At both assessments they were given self-report measures (CES-D, the State Anxiety Inventory, and the State Anger Inventory) and provided urine samples for assays of cortisol, catecholamines (norepinephrine, epinephrine and dopamine) and serotonin. They were also given the VITAS scale for lower back pain and leg pain and a sleep disturbance scale. The stability of mood states and biochemistry across pregnancy (20 and 32 weeks) were assessed inasmuch as mood states, and biochemistry have been noted to predict prematurity and low birthweight. Significant correlations were noted for all variables except serotonin. Relationships between mood states and biochemistry were also noted but only between cortisol and depression, cortisol and anxiety, and epinephrine and anxiety. Significant stability was noted between the 20-week measures and the 32-week measures including depression, anxiety, anger, and cortisol. These were, in turn, correlated with each other and with, low back pain, leg pain, and sleep disturbance. These data suggest the stability of mood states and cortisol across pregnancy.

Original languageEnglish
Pages (from-to)262-267
Number of pages6
JournalInfant Behavior and Development
Volume29
Issue number2
DOIs
StatePublished - Apr 1 2006

Fingerprint

Biochemistry
Hydrocortisone
Depression
Pregnancy
Anxiety
Anger
Low Back Pain
Epinephrine
Epidemiologic Studies
Leg
Serotonin
Sleep
Pain
Equipment and Supplies
Second Pregnancy Trimester
Self Report
Gestational Age
Catecholamines
Pregnant Women
Dopamine

Keywords

  • Biochemistry
  • Depressed pregnant women
  • Mood states

ASJC Scopus subject areas

  • Developmental and Educational Psychology

Cite this

Stability of mood states and biochemistry across pregnancy. / Field, Tiffany M; Hernandez-Reif, Maria; Diego, Miguel A; Schanberg, Saul; Kuhn, Cynthia.

In: Infant Behavior and Development, Vol. 29, No. 2, 01.04.2006, p. 262-267.

Research output: Contribution to journalArticle

Field, Tiffany M ; Hernandez-Reif, Maria ; Diego, Miguel A ; Schanberg, Saul ; Kuhn, Cynthia. / Stability of mood states and biochemistry across pregnancy. In: Infant Behavior and Development. 2006 ; Vol. 29, No. 2. pp. 262-267.
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