TY - JOUR
T1 - Stability constant studies on a new selective chelating agent for mercury(II)
AU - Jones, Mark M.
AU - Banks, Alton J.
AU - Hendricks Brown, C.
N1 - Funding Information:
Ackmm'ledgement This work was performed Under the auspices of the Center of Toxicology, Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37235, and supported by the United States Public Health Services Center Grant ES00267.
PY - 1974/8
Y1 - 1974/8
N2 - A new chelating agent, phthalytetrathioacetic acid, (PTTA), has been characterized and found to be highly selective for Hg2+. All four of its ionization constants have been determined and the stability constants of its complexes with Hg2+, Ca2+, Zn2+, Co2+, Pb2+, Ni2+, and Cd2+ estimated. The mercury complex has a stability constant greater than those of the other complexes by a factor of at least 1010. The high selectivity for the Hg2+ ion is due to a closely spaced group of thioether sulfurs and a rather wide separation of the carboxylic acid groups which are potential members of chelate rings. The mercury complexes present in aqueous solution are Hg(PTTA)H2, log K = 18·8 at low pH and Hg(PTTA) (OH)2, log K = 45 at high pH. The presence of thioether, rather than thiol sulfur atoms has the result that the chelate with Pb2+ is of low stability.
AB - A new chelating agent, phthalytetrathioacetic acid, (PTTA), has been characterized and found to be highly selective for Hg2+. All four of its ionization constants have been determined and the stability constants of its complexes with Hg2+, Ca2+, Zn2+, Co2+, Pb2+, Ni2+, and Cd2+ estimated. The mercury complex has a stability constant greater than those of the other complexes by a factor of at least 1010. The high selectivity for the Hg2+ ion is due to a closely spaced group of thioether sulfurs and a rather wide separation of the carboxylic acid groups which are potential members of chelate rings. The mercury complexes present in aqueous solution are Hg(PTTA)H2, log K = 18·8 at low pH and Hg(PTTA) (OH)2, log K = 45 at high pH. The presence of thioether, rather than thiol sulfur atoms has the result that the chelate with Pb2+ is of low stability.
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U2 - 10.1016/0022-1902(74)80519-1
DO - 10.1016/0022-1902(74)80519-1
M3 - Article
AN - SCOPUS:0346215510
VL - 36
SP - 1833
EP - 1836
JO - Polyhedron
JF - Polyhedron
SN - 0277-5387
IS - 8
ER -