Abstract
We use a two-patch model to address the spread of antibiotic-resistant bacteria (ARB) within and between hospitals. Specifically, we consider patients being referred and transferred from a small community hospital with inappropriate antibiotic use to a large teaching hospital with good antibiotic treatment. Our analyses show that screening and decolonizing patients transferred between hospitals and avoiding misuse of antibiotics are both crucial factors to contain nosocomial infections.
| Original language | English (US) |
|---|---|
| Article number | 106097 |
| Journal | Applied Mathematics Letters |
| Volume | 102 |
| DOIs | |
| State | Published - Apr 2020 |
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Keywords
- Antibiotic resistance
- Backward bifurcation
- Global stability
- Patch model
ASJC Scopus subject areas
- Applied Mathematics
Cite this
Stability and bifurcation analysis of a two-patch SIS model on nosocomial infections. / Feng, Xiaomei; Liu, Lili; Tang, Sanyi; Huo, Xi.
In: Applied Mathematics Letters, Vol. 102, 106097, 04.2020.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Stability and bifurcation analysis of a two-patch SIS model on nosocomial infections
AU - Feng, Xiaomei
AU - Liu, Lili
AU - Tang, Sanyi
AU - Huo, Xi
PY - 2020/4
Y1 - 2020/4
N2 - We use a two-patch model to address the spread of antibiotic-resistant bacteria (ARB) within and between hospitals. Specifically, we consider patients being referred and transferred from a small community hospital with inappropriate antibiotic use to a large teaching hospital with good antibiotic treatment. Our analyses show that screening and decolonizing patients transferred between hospitals and avoiding misuse of antibiotics are both crucial factors to contain nosocomial infections.
AB - We use a two-patch model to address the spread of antibiotic-resistant bacteria (ARB) within and between hospitals. Specifically, we consider patients being referred and transferred from a small community hospital with inappropriate antibiotic use to a large teaching hospital with good antibiotic treatment. Our analyses show that screening and decolonizing patients transferred between hospitals and avoiding misuse of antibiotics are both crucial factors to contain nosocomial infections.
KW - Antibiotic resistance
KW - Backward bifurcation
KW - Global stability
KW - Patch model
UR - http://www.scopus.com/inward/record.url?scp=85074406716&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85074406716&partnerID=8YFLogxK
U2 - 10.1016/j.aml.2019.106097
DO - 10.1016/j.aml.2019.106097
M3 - Article
AN - SCOPUS:85074406716
VL - 102
JO - Applied Mathematics Letters
JF - Applied Mathematics Letters
SN - 0893-9659
M1 - 106097
ER -