Stability and bifurcation analysis of a two-patch SIS model on nosocomial infections

Xiaomei Feng, Lili Liu, Sanyi Tang, Xi Huo

Research output: Contribution to journalArticle

Abstract

We use a two-patch model to address the spread of antibiotic-resistant bacteria (ARB) within and between hospitals. Specifically, we consider patients being referred and transferred from a small community hospital with inappropriate antibiotic use to a large teaching hospital with good antibiotic treatment. Our analyses show that screening and decolonizing patients transferred between hospitals and avoiding misuse of antibiotics are both crucial factors to contain nosocomial infections.

Original languageEnglish (US)
Article number106097
JournalApplied Mathematics Letters
Volume102
DOIs
StatePublished - Apr 2020

Fingerprint

Patient treatment
Backward Bifurcation
SIS Model
Antibiotics
Bifurcation Analysis
Global Stability
Patch
Infection
Stability Analysis
Bacteria
Screening
Teaching

Keywords

  • Antibiotic resistance
  • Backward bifurcation
  • Global stability
  • Patch model

ASJC Scopus subject areas

  • Applied Mathematics

Cite this

Stability and bifurcation analysis of a two-patch SIS model on nosocomial infections. / Feng, Xiaomei; Liu, Lili; Tang, Sanyi; Huo, Xi.

In: Applied Mathematics Letters, Vol. 102, 106097, 04.2020.

Research output: Contribution to journalArticle

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