Spinal cord injury and urinary tract infection: Bacterial resistance in out-patients vs in-patients

A. D. Abentroth, D. D. Cardenas, T. M. Hooton, J. Doctor

Research output: Contribution to journalArticle

Abstract

Urinary tract indections (UTI) constitute a significant clinical problem among spinal cord injured (SCI) patients. We compared bacterial resistance in UTIs of 50 SCI in-patients and 50 SCI out-patients who were between the ages of 18-75, on intermittent catheterization, and treated in the hospital between December 1995 and January 1998. In-patients were selected from those with a hospital stay for greater than one week, and out-patients were selected from those who had frequent UTIs and were followed for at least 6 months using monthly urine samples at the out-patient clinic. A UTI was defined as a significant amount of bacteria in the urine (≥105 col/ml). Medical records of 65 men and 35 women were reviewed. Only one UTI per patient was evaluated. A resistant uropathogen was defined as one resistant to ≥2 antibiotics. The most common causative uropathogens in the in-patients were Klebsiella, Pseudomonas, Escherichia coli, and Euterobacter, wheras the most common causative uropathogens of out-patient infections were Klebsiella, Escherichia coli, Enterococcus, and Pseudomonas. Uropathogens in in-patients were more likely to be resistant than those in out-patients (68% vs. 48%; p<0.05).

Original languageEnglish (US)
Pages (from-to)15A
JournalJournal of Investigative Medicine
Volume47
Issue number2
StatePublished - Feb 1999

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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