Spectral-domain optical coherence tomography documentation of transsynaptic retinal degeneration

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3 Citations (Scopus)

Abstract

Patients with post-geniculate neurologic disease and corresponding visual field loss may have ophthalmologic abnormalities detectable by spectral-domain optical coherence tomography (SD-OCT), presumably by transsynaptic retrograde retinal degeneration. Here, three such patients (ages 13 years through 75 years) illustrate thinning of the macula and ganglion cell complex corresponding to zones of visual field loss. Thinning of the retinal nerve fiber layer is not notable in these patients. SD-OCT may be a useful technique in diagnosing and following patients with post-geniculate neurologic disease.

Original languageEnglish (US)
Pages (from-to)768-772
Number of pages5
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume47
Issue number8
DOIs
StatePublished - Aug 1 2016

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Retinal Degeneration
Optical Coherence Tomography
Documentation
Nervous System Diseases
Visual Fields
Retrograde Degeneration
Nerve Fibers
Ganglia

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

Cite this

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AB - Patients with post-geniculate neurologic disease and corresponding visual field loss may have ophthalmologic abnormalities detectable by spectral-domain optical coherence tomography (SD-OCT), presumably by transsynaptic retrograde retinal degeneration. Here, three such patients (ages 13 years through 75 years) illustrate thinning of the macula and ganglion cell complex corresponding to zones of visual field loss. Thinning of the retinal nerve fiber layer is not notable in these patients. SD-OCT may be a useful technique in diagnosing and following patients with post-geniculate neurologic disease.

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