Spasticity and the use of intrathecal baclofen in patients with spinal cord injury

Seema R. Khurana, Deep S. Garg

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Muscle spasms and spasticity constitute a significant problem in patients with spinal cord injury, interfering with rehabilitation and leading to impairments in quality of life in addition to medical complications. Administration of intrathecal baclofen (ITB) is indicated when spasticity continues to produce a clinical disability despite trials of oral treatments and other alternatives in patients who have functional goals and/or pain without contractures. Severe spasticity of spinal origin has been shown to respond dramatically to long-term ITB when used in appropriate patients with spasticity.

Original languageEnglish (US)
Pages (from-to)655-669
Number of pages15
JournalPhysical Medicine and Rehabilitation Clinics of North America
Issue number3
StatePublished - Aug 2014


  • Baclofen
  • Spasms
  • Spasticity
  • Tone

ASJC Scopus subject areas

  • Rehabilitation
  • Physical Therapy, Sports Therapy and Rehabilitation


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