Sources of stem cells for regenerative medicine

Jennifer Hipp, Anthony Atala

Research output: Contribution to journalArticle

144 Citations (Scopus)

Abstract

The shortage of organ donors for regenerative medicine has stimulated research on stem cells as a potential resource for cell-based therapy. Stem cells have been used widely for regenerative medicine applications. The development of innovative methods to generate stem cells from different sources suggests that there may be new alternatives for cell-based therapies. Here, we provide an overview of human embryonic stem cells (hES) and the methods for obtaining these cells and other broadly multipotent or pluripotent cell types. These methods include somatic cell nuclear transfer, single cell embryo biopsy, arrested embryos, altered nuclear transfer, and reprogramming somatic cells. We also discuss the use of amniotic-fluid derived stem cells (AFS) for potential patient-specific therapies.

Original languageEnglish
Pages (from-to)3-11
Number of pages9
JournalStem Cell Reviews
Volume4
Issue number1
DOIs
StatePublished - Mar 1 2008
Externally publishedYes

Fingerprint

Regenerative Medicine
Stem Cells
Cell- and Tissue-Based Therapy
Single Embryo Transfer
Stem Cell Research
Amniotic Fluid
Embryonic Structures
Tissue Donors
Biopsy

Keywords

  • Human embryonic stem cells
  • Patient-specific therapy
  • Stem cells

ASJC Scopus subject areas

  • Transplantation
  • Immunology
  • Cell Biology

Cite this

Sources of stem cells for regenerative medicine. / Hipp, Jennifer; Atala, Anthony.

In: Stem Cell Reviews, Vol. 4, No. 1, 01.03.2008, p. 3-11.

Research output: Contribution to journalArticle

Hipp, Jennifer ; Atala, Anthony. / Sources of stem cells for regenerative medicine. In: Stem Cell Reviews. 2008 ; Vol. 4, No. 1. pp. 3-11.
@article{02d42c6b48c946ceb648f47c897ff480,
title = "Sources of stem cells for regenerative medicine",
abstract = "The shortage of organ donors for regenerative medicine has stimulated research on stem cells as a potential resource for cell-based therapy. Stem cells have been used widely for regenerative medicine applications. The development of innovative methods to generate stem cells from different sources suggests that there may be new alternatives for cell-based therapies. Here, we provide an overview of human embryonic stem cells (hES) and the methods for obtaining these cells and other broadly multipotent or pluripotent cell types. These methods include somatic cell nuclear transfer, single cell embryo biopsy, arrested embryos, altered nuclear transfer, and reprogramming somatic cells. We also discuss the use of amniotic-fluid derived stem cells (AFS) for potential patient-specific therapies.",
keywords = "Human embryonic stem cells, Patient-specific therapy, Stem cells",
author = "Jennifer Hipp and Anthony Atala",
year = "2008",
month = "3",
day = "1",
doi = "10.1007/s12015-008-9010-8",
language = "English",
volume = "4",
pages = "3--11",
journal = "Stem Cell Reviews and Reports",
issn = "1550-8943",
publisher = "Humana Press",
number = "1",

}

TY - JOUR

T1 - Sources of stem cells for regenerative medicine

AU - Hipp, Jennifer

AU - Atala, Anthony

PY - 2008/3/1

Y1 - 2008/3/1

N2 - The shortage of organ donors for regenerative medicine has stimulated research on stem cells as a potential resource for cell-based therapy. Stem cells have been used widely for regenerative medicine applications. The development of innovative methods to generate stem cells from different sources suggests that there may be new alternatives for cell-based therapies. Here, we provide an overview of human embryonic stem cells (hES) and the methods for obtaining these cells and other broadly multipotent or pluripotent cell types. These methods include somatic cell nuclear transfer, single cell embryo biopsy, arrested embryos, altered nuclear transfer, and reprogramming somatic cells. We also discuss the use of amniotic-fluid derived stem cells (AFS) for potential patient-specific therapies.

AB - The shortage of organ donors for regenerative medicine has stimulated research on stem cells as a potential resource for cell-based therapy. Stem cells have been used widely for regenerative medicine applications. The development of innovative methods to generate stem cells from different sources suggests that there may be new alternatives for cell-based therapies. Here, we provide an overview of human embryonic stem cells (hES) and the methods for obtaining these cells and other broadly multipotent or pluripotent cell types. These methods include somatic cell nuclear transfer, single cell embryo biopsy, arrested embryos, altered nuclear transfer, and reprogramming somatic cells. We also discuss the use of amniotic-fluid derived stem cells (AFS) for potential patient-specific therapies.

KW - Human embryonic stem cells

KW - Patient-specific therapy

KW - Stem cells

UR - http://www.scopus.com/inward/record.url?scp=50849106701&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=50849106701&partnerID=8YFLogxK

U2 - 10.1007/s12015-008-9010-8

DO - 10.1007/s12015-008-9010-8

M3 - Article

C2 - 18286392

AN - SCOPUS:50849106701

VL - 4

SP - 3

EP - 11

JO - Stem Cell Reviews and Reports

JF - Stem Cell Reviews and Reports

SN - 1550-8943

IS - 1

ER -