Source of Androgen in Hirsute Women

Arthur G. Shapiro, Robert L. Rosenfield, Marvin A. Kirschner

Research output: Contribution to journalLetterpeer-review

Abstract

To the Editor: In reference to the article, “Idiopathic Hirsutism,” by Kirschner et al. (N Engl J Med 294:637, 1976), it would be interesting to try to explain the dexamethasone suppression on the ovarian androgens by its effect on the metabolic clearance rates âi.e., by the increase in the metabolic clearance of testosterone. One of the effects of dexamethasone is to increase metabolic clearance rate, and it was of interest to find that the metabolic clearance rates of patients who did not respond were already elevated. One could therefore hypothesize Chat there is a form of the ovarian hirsutism.

Original languageEnglish (US)
Pages (from-to)231-233
Number of pages3
JournalNew England Journal of Medicine
Volume295
Issue number4
DOIs
StatePublished - Jul 22 1976

ASJC Scopus subject areas

  • Medicine(all)

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