Some physiologic and hemodynamic observations in ventricular septal defect*

Otto García, Heriberto Mercado, Alberto H. Cañero, Agustin Castellanos, Frank Barrera, The Technical Assistance of Francisco Zerquera With The Technical Assistance of Francisco Zerquera

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The hemodynamic data of eighty-two patients with ventricular septal defect are presented. A drop in systolic pressure between the right ventricle and pulmonary artery trunk was present in sixty-four patients. The largest gradient found was 25 mm. Hg. We believe this gradient does not represent an associated pulmonary stenosis but is due rather to functional effects. Analysis of the hemodymanic data suggests that the size of the ventricular septal defect is the principal factor determining the various changes. In smaller septal defects, the magnitude of the left-to-right shunt is a function of the size of the hole. Pulmonary resistance determines the magnitude of the left-to-right shunt in larger defects. The presence or absence of a right-to-left shunt depends on right ventricular pressure. The mechanism by which changes in the pulmonary resistance occur remains unknown.

Original languageEnglish (US)
Pages (from-to)167-175
Number of pages9
JournalThe American journal of cardiology
Volume5
Issue number2
StatePublished - Feb 1960
Externally publishedYes

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Ventricular Heart Septal Defects
Hemodynamics
Lung
Pulmonary Valve Stenosis
Ventricular Pressure
Pulmonary Artery
Heart Ventricles
Blood Pressure

ASJC Scopus subject areas

  • Medicine(all)
  • Cardiology and Cardiovascular Medicine

Cite this

García, O., Mercado, H., Cañero, A. H., Castellanos, A., Barrera, F., & With The Technical Assistance of Francisco Zerquera, T. T. A. O. F. Z. (1960). Some physiologic and hemodynamic observations in ventricular septal defect* The American journal of cardiology, 5(2), 167-175.

Some physiologic and hemodynamic observations in ventricular septal defect* . / García, Otto; Mercado, Heriberto; Cañero, Alberto H.; Castellanos, Agustin; Barrera, Frank; With The Technical Assistance of Francisco Zerquera, The Technical Assistance of Francisco Zerquera.

In: The American journal of cardiology, Vol. 5, No. 2, 02.1960, p. 167-175.

Research output: Contribution to journalArticle

García, O, Mercado, H, Cañero, AH, Castellanos, A, Barrera, F & With The Technical Assistance of Francisco Zerquera, TTAOFZ 1960, 'Some physiologic and hemodynamic observations in ventricular septal defect* ', The American journal of cardiology, vol. 5, no. 2, pp. 167-175.
García O, Mercado H, Cañero AH, Castellanos A, Barrera F, With The Technical Assistance of Francisco Zerquera TTAOFZ. Some physiologic and hemodynamic observations in ventricular septal defect* The American journal of cardiology. 1960 Feb;5(2):167-175.
García, Otto ; Mercado, Heriberto ; Cañero, Alberto H. ; Castellanos, Agustin ; Barrera, Frank ; With The Technical Assistance of Francisco Zerquera, The Technical Assistance of Francisco Zerquera. / Some physiologic and hemodynamic observations in ventricular septal defect* In: The American journal of cardiology. 1960 ; Vol. 5, No. 2. pp. 167-175.
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