Solitary fibrous tumor of the liver: A case report, review of the literature and differential diagnosis of spindle cell lesions of the liver

Pablo A. Bejarano, Ramon Blanco, Douglas W. Hanto

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

A rare case of solitary fibrous tumor (SFT) of the liver is described. The patient was a 49-year-old man who had a 17x12x10 cm mass (2,750 g) with a firm and vaguely whorled cut surface, a scar-like central area, and pushing rather than infiltrating borders. It was located in the subcapsular parenchyma of the left lobe. The histologic, immunohistochemical, and ultrastructural features are identical to those seen in the more common SFTs of the pleura. Those features include a variable spindle cell proliferation, scant mitotic activity, immunoreactivity for CD34 and vimentin, and the absence of necrosis. The patient underwent a partial hepatectomy and the surgical margins were free of tumor. No recurrence was detected 15 months after excision. This case adds to 12 similar previously reported cases involving the liver. A review of the literature indicates that SFT of the liver behaves in a benign fashion.

Original languageEnglish (US)
Pages (from-to)93-100
Number of pages8
JournalInternational Journal of Surgical Pathology
Volume6
Issue number2
DOIs
StatePublished - Apr 1998

Keywords

  • CD34
  • Fibroma
  • Fibrous mesothelioma
  • Immunohistochemistry
  • Liver
  • Solitary fibrous tumor

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine
  • Surgery

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